In a new study seen in Cell, scientists at CiRA show unexpectedly that small levels of turbulence in the blood promotes the generation of platelets, the cells responsible for wound healing.
Using this new information, they report a bioreactor that produces more than 100 billion platelets from iPS cells, a number that can be used to treat patients.
Blood transfusions are the oldest form of cell therapy and have been done for centuries.
However, platelets taken from donors can only be stored for several days, which is why organizations like the Red Cross hold regular blood drives.
While this approach is the global standard, with the number of aging populations increasing, many nations are anticipating severe donor shortages.
Japan alone estimates that its platelet supplies will serve only four of every five patients in the next decade.