BOSTON, FEBRUARY 13 - A group of leading scientists devoted to research on the mechanisms of biological aging today announced the formation of the Academy for Health and Lifespan, the first global non-profit group focused on accelerating breakthroughs in the expansion of the human health span.The timing of the announcement aligns with the Valentine's Day holiday to call attention to the Academy for Health and Lifespan Research mission to enable people to live better and love longer.The group's plan is to accomplish its goals through awareness and education, by giving new research a platform for dissemination, and by organizing conferences and forums where the world's leaders in the study of health span and longevity will gather and share research and insights."We believe we are at a threshold moment in the research of age-related decline, which is the timing that inspired the creation of the Academy," said David Setboun, chair and president of the new Academy for Health and Lifespan Research.The complete list of Founders is attached.Finally, we shall communicate with the public at large to educate them about this new generation of health span and longevity research, what it means and what it doesn't mean, and to engage in constructive conversations.
"I would explain texting first, and how it takes five minutes now for people to decide they want to hook up," says comedian Nikki Glaser."I would tell women, 'Buckle up, bitch, this is not going to be a fun ride.'"Today's relationships can strike up after a few minutes of text chats.The internet has been "transformational" to the way we have relationships, says Pepper Schwartz, a professor of sociology at the University of Washington who studies dating and is also one of the matchmaking experts on the reality TV show Married at First Sight.(Schwartz said researchers could tell because children weren't getting married in order of oldest to youngest anymore.)Who hasn't read about how millennials are less religious, have fewer kids and, despite the popularity of Tinder and the less formal dating culture it's helped introduce, may even be having less sex?
Apparently not the folks behind Seattle-based startup Atomo.They recently took to Kickstarter with their promise of a “molecular coffee,” offering the great taste of a cup of Joe, minus the need for a single harvested coffee bean.“I was searching for my next new startup idea, and I had one requirement: it must be something that makes the world a better place,” Andy Kleitsch, CEO and co-founder of Atomo, told Digital Trends.“I started researching coffee production, [which turns out to be] in serious trouble.With climate change, half of all coffee plantations will no longer support coffee growth in 30 years.Climate change is leading to further deforestation, as coffee plantations continue ‘up-farming,’ a practice whereby plantations clear the forestlands higher in elevation to grow more coffee.
Seattle’s far from a nascent startup ecosystem, but despite the presence of tech giants like Microsoft and Amazon, the city still lags behind other tech ecosystems like Boston and New York City in terms of venture capital raised.Today, the University Washington Bothell and Seattle-based advisory firm Iinnovate Leadership Network released their annual report on the health of Seattle’s startup and tech ecosystem.First, the good news: according to Iinnovate, Seattle’s VC firms raised the most new funds in 2018 than they had in any other year for about the last 10 years.However, it’s coming as Seattle startups continue to struggle to raise seed stage funding.VentureBeat’s Heartland Tech channel invites you to join senior business leaders at BLUEPRINT in York, Pennsylvania on March 26-28.And, as Washington, D.C., New York City, and Nashville to a lesser extent hope that the arrival of Amazon will help their tech community grow, Seattle’s ecosystem shows that Amazon’s arrival might not help them in all the ways their tech leaders think it will.
CHAMPAIGN, Ill. -- The trucks and trains that transport goods across the United States emit gases and particles that threaten human health and the environment.A University of Illinois-led project developed a new model that predicts through 2050 the impact of different environmental policies on human mortality rates and short- and long-term climate change caused by particulate and greenhouse gas emissions.Greenhouse gas and some particulate matter emissions cause the atmosphere to heat up, but at different rates, said Tami Bond, a civil and environmental engineering professor who led the study with graduate student Liang Liu."Particulate matter washes out of the atmosphere quickly, making its effect on climate short-lived - unlike greenhouse gases that stay in the atmosphere for decades.Civil and environmental engineering professor Yanfeng Ouyang and urban and regional planning professor Bumsoo Lee collaborated to make the modeled projections possible, along with researchers from the University of Washington, Pennsylvania State University, the Pacific Northwest National Laboratory and Argonne National Laboratory.The researchers used what they call a "system of systems" approach to model how the increased volume of shipping, mode of transport, population density and environmental policies will factor into the future health and climate impacts of land freight.
The image of a lab rat is an iconic symbol of scientific research, and for good reason: These rodents are remarkably good stand-ins for human subjects because of how closely their physiology and genetic make-up resemble ours.Because of this, mice and rats are used to study everything from cancer to diabetes to Alzheimer’s disease.However, despite their tried-and-true use as animal models, there’s something about these rodents that puzzles scientists: What is all the squeaking about?Up until now, researchers have relied heavily on ambiguous physical cues—such as rats pressing a lever to receive a dose of an addictive substance—or time-consuming manual analysis of rodent chatter to try to understand what drives their behaviour during trials.Both of these methods are vulnerable to human error and misinterpretation.Similar to how a self-driving car might take in and evaluate visual data from the road in front of it, DeepSqueak transforms audio recordings of rodent calls into sonogram images and then uses machine vision to analyse them.
In a typical conductor, electrical current flows everywhere.Insulators, on the other hand, do not readily conduct electricity.Topology is the mathematical study of the properties of a geometric figure or solid that is unchanged by stretching or bending.Applying this concept to electronic materials leads to discoveries of many interesting phenomena, including topological edge conduction.Working like highways for electrons, channels of topological edge conduction allow electrons to travel with little resistance.Several recent experiments established that monolayer WTe2 is the first atomically thin 2-D topological insulator."
Less than a year into its mission, a sky-survey camera in Southern California shows just how full the sky is.The Zwicky Transient Facility, based at the Palomar Observatory in San Diego County, has identified over a thousand new objects and phenomena in the night sky, including more than 1,100 new supernovae and 50 near-Earth asteroids, as well as binary star systems and black holes.Operated by Caltech, the ZTF is a public-private partnership between the National Science Foundation and a consortium of nine other institutions around the globe, including the University of Washington.The ZTF collaboration's six latest papers, which describe these discoveries as well as the ZTF's data mining, sorting and alert systems, have been accepted for publication in the journal Publications of the Astronomical Society of the Pacific.Eric Bellm, the ZTF survey scientist and a research assistant professor of astronomy at UW, is lead author on a paper describing the ZTF's technical systems and major findings since the survey began on March 20, 2018.Maria Patterson, a data scientist formerly with the UW Department of Astronomy's DIRAC Institute, is lead author on another paper describing the ZTF's alert system for notifying science teams of possible new objects in the sky or significant changes to existing objects.
Animating your kinematic systems before and during assembly helps to understand interactions, point out inconsistencies or potential points of failure, and even selling the machine to key stakeholders before completion.You’re not just aiming to showcase an environment in action, but also looking to understand complexities that are otherwise impossible to estimate.In their treatment of complex machinery systems and the nuances require to animate them, researchers from the University of Washington and the University of Wyoming make an important distinction between kinematic and dynamic machinery systems:For kinematic machinery systems, the reaction force problem is uncoupled from the motion problem.That distinction underscores just some of the complexities that come with machine concept drawings and prototypes.3) Training and Assembly Directions
Advances in stem cell research offer hope for treatments that could help patients regrow heart muscle tissue after heart attacks, a key to achieving more complete recovery.Scientists today report success in creating functional blood vessels in vitro for hearts of rats that had sustained a heart attack.The journal Nature Communications published the paper, whose lead authors are Ying Zheng and Charles Murry of the UW Medicine Institute for Stem Cell and Regenerative Medicine in Seattle."To our knowledge, this is the first demonstration that building organized blood vessels with perfusion outside the body leads to improved integration with host blood vessels and better tissue blood flow," said Zheng, a University of Washington associate professor of bioengineering.The scientists set out to show that by growing stem cell-derived heart tissue in a petri dish, with attention to blood vessels' construction, they could improve the tissue's incorporation with existing heart vessels."I come from a mechanical background," Zheng continued.
The revamped versions were developed and tested at UW Medicine labs in animal models of muscular dystrophy.The results will be published Feb. 1 in Molecular Therapy, a Cell Press journal.The treatment-carrying vehicles are re-tooled from small, adeno-associated viruses.These repurposed viruses can still enter human cells.Adeno-associated viruses do not cause infections, but can evoke an immune response that is usually mild.Jeffrey S. Chamberlain, professor of neurology, medicine and biochemistry at the University of Washington School of Medicine, has been continuously involved in this research, from the invention of his lab's original gene therapy cassettes to their recent revamping.
Looking at the Chronicle of Philanthropy's top 50 philanthropists list for 2017, 60% of the people on the list are from the technology industry.2018 net worth: $38.4 billionHow he made his billions: Ballmer is a former CEO at Microsoft who joined the company early on as its 30th employee.Donations made: Ballmer and his wife run the Ballmer Group, a charity that focuses on "efforts to improve economic mobility for children and families in the United States who are disproportionately likely to remain in poverty."The Ballmers' foundation has pledged millions to Harvard University, the University of Washington, and the University of Oregon.2018 net worth: $39 billion
Scientists seeking to capture and control on Earth fusion energy, the process that powers the sun and stars, face the risk of disruptions -- sudden events that can halt fusion reactions and damage facilities called tokamaks that house them.Researchers at the U.S. Department of Energy's (DOE) Princeton Plasma Physics Laboratory (PPPL), and the University of Washington have developed a novel prototype for rapidly controlling disruptions before they can take full effect.The device, called an "electromagnetic particle injector" (EPI), is a type of railgun that fires a high-velocity projectile from a pair of electrified rails into a plasma on the verge of disruption.The projectile, called a "sabot," releases a payload of material into the center of the plasma that radiates, or spreads out, the energy stored in the plasma, reducing its impact on the interior of the tokamak.Current systems release pressurized gas or gas-propelled shattered pellets using a gas valve into the plasma, but with velocity limited by the mass of the gas particles."The primary advantage of the EPI concept over gas-propelled systems is its potential to meet short-warning time scales," said Roger Raman, a University of Washington physicist on long-term assignment to PPPL and lead author of a Nuclear Fusion paper that describes the new system.
"AI is evolving rapidly, and as a society we're still trying to understand its impact - both in terms of its benefits and its unintended consequences," said conference co-chair Vincent Conitzer, of Duke University."The AIES conference was designed to include participation from different disciplines and corners of society, in order to offer a unique and informative look at where we stand with the development and the use of artificial intelligence."The AIES conference was chaired by a multi-disciplinary program committee to ensure a diversity of topics.Conference sessions will address algorithmic fairness, measurement and justice, autonomy and lethality, human-machine interaction and AI for social good, among other focuses.The conference is sponsored by the Berkeley Existential Risk Initiative, DeepMind Ethics and Society, Google, National Science Foundation, IBM Research, Facebook, Amazon, PWC, Future of Life Institute, and the Partnership on AI.Athey will address theoretical perspectives on how organizations should guide and implement AI in a way that is fair and that achieves the organization's objectives.
Nvidia today opened its robotics research lab, a 13,000-foot facility in Seattle.The lab will house 50 roboticists, 20 from Nvidia Research staff, and others from the wider academic research community.Dieter Fox, a member of University of Washington computer science faculty, is the director of the lab.The lab was intentionally opened in Seattle to be close to knowledgable people from the University of Washington such as Human-Centered Robotics Lab director Maya Cakmak.The lab officially opened last November but moved to its permanent headquarters today.Among the facility’s offerings is an Ikea kitchen where experiments will be conducted.
But some stars can go supernova simply because they have a close and pesky companion star that, one day, perturbs its partner so much that it explodes.Through repeated observations of SN 2015cp, a supernova 545 million light years away, the team detected hydrogen-rich debris that the companion star had shed prior to the explosion."The presence of debris means that the companion was either a red giant star or similar star that, prior to making its companion go supernova, had shed large amounts of material," said University of Washington astronomer Melissa Graham, who presented the discovery and is lead author on the accompanying paper accepted for publication in The Astrophysical Journal.The supernova material smacked into this stellar litter at 10 percent the speed of light, causing it to glow with ultraviolet light that was detected by the Hubble Space Telescope and other observatories nearly two years after the initial explosion.By looking for evidence of debris impacts months or years after a supernova in a binary star system, the team believes that astronomers could determine whether the companion had been a messy red giant or a relatively neat and tidy star.Carbon-oxygen white dwarfs are small, dense and -- for stars -- quite stable.
Photo by Mark Stone / University of WashingtonScientists have built an app that gives a smartphone the ability to detect an opioid overdose and alert others for help.The app, called Second Chances, is still in development, but the researchers hope to have it approved by the US Food and Drug Administration and eventually sell the technology.With over 110 Americans dying each day from opioid overdoses, the opioid epidemic is the deadliest drug overdose crisis in US history.“It’s a huge public health problem and also one where the diagnostic signs and mechanisms of how people die is really well-established,” says Jacob Sunshine, an anesthesiologist at the University of Washington and co-author of the Second Chances study, which was published this week in the journal Science Translational Medicine.In other words, when people overdose, their breathing changes in a specific and predictable pattern.
At least 115 people die every day in the U.S. after overdosing on opioids, according to the National Institute on Drug Abuse.And in 2016, illegal injectable opioids became the most common drug involved in overdose-related deaths.The team will publish its results Jan. 9 in Science Translational Medicine."The idea is that people can use the app during opioid use so that if they overdose, the phone can potentially connect them to a friend or emergency services to provide naloxone," said co-corresponding author Shyam Gollakota, an associate professor in the UW's Paul G. Allen School of Computer Science & Engineering."Here we show that we have created an algorithm for a smartphone that is capable of detecting overdoses by monitoring how someone's breathing changes before and after opioid use."The Second Chance app sends inaudible sound waves from the phone to people's chests and then monitors the way the sound waves return to the phone to look for specific breathing patterns.
IL-2 is a potent anticancer drug and an effective treatment for autoimmune disease, but its toxic side effects have limited its clinical usefulness.In a paper in the Jan. 10 issue of the journal Nature, the researchers report using computer programs to design a protein that they have shown in animal models to have the same ability to stimulate cancer-fighting T-cells as the naturally occurring IL-2, but without triggering harmful side effects.The achievement opens new approaches to the design of protein-based therapeutics for the treatment of cancer, autoimmune diseases and other disorders, the researchers said.The new protein has been dubbed Neo-2/15 because, in addition to mimicking the effect of IL-2, the protein can also mimic the effect of another interleukin, IL-15, which is being studied as another possible anticancer immunotherapy."People have tried for 30 years to alter IL-2 to make it safer and more effective, but because naturally occurring proteins tend not to be very stable, this has proved to be very hard to do," said a lead author of the paper, Daniel-Adriano Silva, an IPD biochemist.Because we designed it from scratch, we understand all its parts, and we can continue to improve it making it even more stable and active."
On Wednesday, Amazon CEO Jeff Bezos announced his plans to file for divorce from MacKenzie Bezos.Divorce experts say many couples prefer to wait until after the holidays have passed to announce their decision.Bezos is the founder and CEO of Amazon, and his estimated net worth is $137 billion.Shaw in New York; they've been married 25 years and have four children together.Interestingly, January has been unofficially labeled "Divorce Month."Researchers at the University of Washington, Julie Brines and Brian Serafini, analyzed divorce filings between 2001 and 2015 in Washington State (where the Bezoses live) and found that they consistently peaked in March and August, i.e.