David Rodriguez

David Rodriguez

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A new method has been developed to make drugs 'smarter' using nanotechnology so they will be more effective at reaching their target.Scientists from the University of Lincoln, UK, have devised a new technique to 'decorate' gold nanoparticles with a protein of choice so they can be used to tailor drug to more accurately target an area on the body, such as a cancer tumour.Gold nanoparticles are spheres made of gold atoms having a diameter of only few billionths of a metre which can be coated with a biological protein and combined with drugs to enable the treatment to travel through the body and reach the affected area.The nanoparticles can 'adsorb' (hold on its surface) drugs which would otherwise become insoluble or quickly degrade in the blood stream, and due to their small size they can overcome biological barriers such as membranes, skin and the small intestine which would usually prevent the drug from reaching its target.The technology is already used in real world applications such as pregnancy tests - where gold nanoparticles decorated with an antibody against the hormone present in the urine of pregnant women is added to the 'positive' strip so it reacts with the nanoparticles to turn the stick red - but is not yet widely used in drug development.Until now the process of coating the nanoparticles meant that the proteins used had to be 'mixed' together with particles which do not have the ability to control the way they bind, possibly making the drug less effective.
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China
If you once had any doubts about Meizu’s ability to deliver on its 15th-anniversary devices, we would urge you to consider them assuaged.The company at its Sunday event not only proved that it wasn’t disturbed by the recent onslaught of Android phones with notched screens with the Meizu 15 trio but also introduced two new products for music lovers – the Meizu POP Wireless Earbuds and the Meizu Halo Laser Earphones.Much like the Gear IconX 2018 and the Apple Airpod, the Meizu OP Wireless earbuds are cord-free accessories with water-resistant earbuds body that weighs about 5.8g.The Meizu POP connects via Bluetooth and comes with touch-sensitive controls with which you can answer/reject calls, pause, play, change songs, or even wake the Meizu Voice Assistant on supported devices.The accessory is available only in white color and is packed in a matching case that doubles as a charger which can be recharged via a USB type C port or on a wireless pad.While the white matching case boasts can provide up to 12 hours of battery life via its built-in 7000mAh battery, the earbud itself comes with an in-built 85mAh battery boasting up to 3 hours on a single charge.
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You know two-factor authentication tokens, the ephemeral, six-digit numbers you use as a second layer of security when logging into, say, your email?But for some time now, I've harbored a pet conspiracy theory about those codes: Maybe they aren't as random as we're led to believe.It began with an observation: My codes often seem to include elements that make them easier to remember.Elements like single-digit repeats (111 293; 134 441); multi-digit repeats (112 222); palindromes (353 595); ascending or descending sequences (345 564); repeating number order (618 514); and combinations thereof (876 565).And when I asked cognitive psychologist Marisca Milikowski, an expert in people's knowledge of numbers, she said she'd noticed it too.In a follow-up study, Milikowski found that, in a short-term memory task, test subjects were not only more likely to correctly recall all the numbers from the good list than the bad list; they were also far more inclined to misremember numbers from the "bad" list, recalling different Other answers like 63, 19, 83, and 79.
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A voice-controlled oven, a TV that doubles as art or an indoor garden that practically manages itself -- it all sounds amazing.There are some things you should consider, however, before diving into a smart home of your own.Here are four of the most important.You'll need to decide on a 'brain' firstWithout a doubt, the biggest concern is fragmentation.It's certainly gotten better over the last few years, especially with the growing popularity of smart speakers like Google Home and Alexa, and services like IFTTT that help fix the language barrier between different devices and services.
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Scientists and engineers at Swansea University have been awarded a research grant by the UK Engineering and Physical Sciences Research Council (EPSRC) that will see them explore highly novel forms of physical photovoltaic (PV) tiles that can be placed on buildings, objects and even clothes.The three-year project involves a range of local and global partners.Dr Ben Masheder of DST Innovations, based in Bridgend, Wales, said; "We believe that the surface has barely been scratched of integrated devices such as sensors, displays, energy harvesting and lighting.This project brings together all of these elements and will go a long way to addressing the challenges that this area presents and because of these we are excited to be a partner in the research."Further afield, the team will work with IIT-B in Mumbai, India; Prof Anirudha Joshi of the Industrial Design Centre said: "The energy demands the internet of things revolution brings are enormous.In the 'developed' world, this problem will affect sustainability.
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The origin story has gone from urban legend to the Oxford dictionary: A group of high school stoners in Northern California in the ’70s birthed the concept of 4/20, and their friendship with the Grateful Dead helped turn an afternoon burnout activity into a legitimate (though illicit at the time) movement.Now 4/20 is an unofficial national holiday, gathering steam as states across the country continue to legalize marijuana for recreational sales.There aren’t any Hallmark cards to commemorate it (yet) but there are plenty of ways to celebrate, from the High Times Cannabis Cup (in suburban Los Angeles) to the Mile High Block Party and Snoop Dogg’s Wellness Retreat (Denver) to far too many Cheech & Chong movie marathons to count.For the past several years, they’ve been sidling up to the April smoke day as a means to get close to the millennial cool kids—and maybe their Gen X parents and boomer grandparents.But so far they’re keeping it light, possibly to diffuse any potential backlash.Mainstream companies aren’t far behind.
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Audible CEO Don Katz said that he bonded with Amazon CEO Jeff Bezos over a strange obsession with serving customers.AudibleAudible CEO Don Katz founded the digital audiobook company in 1995, launched with one of the world's first digital audio players.Katz sold Audible to Amazon in 2008 for $300 million, keeping it largely independent and retaining his role as CEO.Katz has been running a tech company for over a decade, and he got his master's in economics in the '70s.Check out previous episodes with:Planned Parenthood president Cecile Richards
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China
And while we wait for Meizu to unveil their brand new handset,the Meizu 15 on the much-anticipated launch event on April 22,just today we caught a glimpse of some images captured by the upcoming device.According to the company their new flagship will be equipped with the best camera technology in a Meizu handset to date.And a pair of leaked photos comes… to confirm this.Having a look at the official camera photos taken from the device’s dual camera, we can see that all in all the Meizu 15 produces photos with more vivid colors, higher resolution, and greater depth of field.Its dual-rear camera that we previously learned about simulates the binocular vision of humans, helping to better capture three-dimensional images.One of the key features of the Meizu 15 camera is that it automatically differentiates between day and night, and optimally adjusts settings, in order to snap the best possible photo in each scenario.
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A deceivingly heavy bag of groceries in one hand, two gallons of milk in the other and newly bloomed daffodils that smell of spring in abundance balancing in the crevice of my right elbow.If anyone deserves a smile, she does.I can’t help but notice it opens reluctantly, after undo-ing three sets of security locks, if I counted correctly.She must feel like she’s opening the door to a cheerful stranger holding milk and flowers.“Hi Nana, it’s me, sorry I’m late.The hippocampus withers away and as much as it fights back, it’s a losing battle.
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A recent change to Google’s App Engine will discontinue a practice called domain-fronting, an essential technique used by dozens of internet freedom tools designed to allow users to work around state-level internet censorship.The update in Google’s network architecture, first spotted by developers of privacy-minded web browser Tor and reported by The Verge, removes a approach counted on by services like encrypted messaging platform Signal, anti-Chinese censorship tool GreatFire.org, and VPN services offered by Psiphon.Domain fronting is used to bypass censors by hiding the true endpoint of a connection.Instead of allowing a service to directly communicate with a server, allowing for the potential that state-level internet censors might identify and block the connection, the request is forwarded through an innocuous domain or IP address range — in this case, Google App Engine.This allows services that would otherwise have their traffic blocked skate under the censors by appearing to come from Google.“Domain fronting has never been a supported feature at Google, but until recently it worked because of a quirk of our software stack,” a spokesperson for Google told Gizmodo.
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Amazon is no different, and back in 2014 it filed a patent for a 'Streaming Data Marketplace' that would allow it to collect online data streams, analyse the data, and after combining multiple streams together they could sell it off to someone else.That may sound complicated and boring, but TechSpot noticed a clause within the patent that might cause some concern over Bitcoin and cryptocurrency enthusiasts, plus anyone with grand plans for blockchain-based security.That's because the patent also outlines a method for analysing Bitcoin's blockchain, with the goal of connecting transactions and Bitcoin addresses with the person who actually made them.Following that the patent specifically mentions selling that data to government agencies and help then identify people involved in the transaction.While Bitcoin has often be lauded as a more secure and privacy-focused way to transfer money, it was never developed to be anonymous.While not as relevant to this discussion, it's worth mentioning that Bitcoin is a bit more unstable than other cryptos which certainly hasn't helped.
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We’ve written a lot about blockchain, the technology that makes Bitcoin possible without any centralized authority.The underlying theme has been its tremendous potential to impact our industry.AdLedger, a non-profit consortium building and implementing blockchain standards for digital advertising, is dedicated to making that happen, along with IBM and Salon Media.The three companies have teamed up for a shared ledger to bring 100% transparency to advertising, beginning with education.“We’ve got super smart people leading the biggest companies in the industry, but they’re not engineers,” explains Christiana Cacciapuoti, Executive Director of AdLedger.The other aspect centers on helping companies make informed decisions about how to implement that.
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Maya Jama has issued an apology after an offensive tweet about “dark skinned women” was unearthed on her Twitter.The Radio 1 presenter was on the receiving end of a backlash when it was revealed she posted on her account back in 2012: “Dark skin bitches shaving their head expecting to look like Amber Rose, when really they end up looking like Micheal Jordan.” Looooooooool.”Maya has since broken her silence on social media to give her “genuine and sincerest apologies”, claiming she had been quoting someone else.She wrote: “A tweet has been brought up from 2012 where I quoted an insensitive joke I saw a comedian say on my timeline.“It was a stupid joke that I shouldn’t have made light of – especially because it’s offensive to a group of women who I know constantly deal with disrespect.“My genuine and sincerest apologies go out, not just to dark skinned women but to ALL women.
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On Sunday, eight firefighters will tie up their laces and join more than 40,000 runners taking part in the London Marathon.The team, from North Kensington fire station, were the first crew on the scene at the Grenfell Tower fire last June.Since then they’ve grieved with the community.But now, they say, it’s time to “heal and re-build”.They hope to raise £50,000 for children who survived or were impacted by the tragedy so they can access crucial services like counselling, alongside lighter relief in the form of discos, dance classes, art therapy and parties.“Everyone at North Kensington Fire Station would love the children of our community to grow up with their lives defined by happy times and achievements, not by a tragedy,” reads the team’s JustGiving page.
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Google, apparently unsatisfied with the already incredibly long list of short-lived communications solutions that it has produced, is taking one more shot messaging.But more importantly, it will hopefully help Google finally solve the seemingly unaccomplishable goal of *checks notes* sending text messages.Instead of building another goddamn app, which the company has done countless times already to middling success, this time Google is aiming to adopt a new standard for messaging that will move users away from SMS.In order to accomplish this, Google has quietly been lobbying major mobile carriers to adopt a new technology, called Rich Communication Services (RCS).Chat is essentially just the consumer-friendly face slapped atop the stuffy name given to the communication protocol.Chat will be accessible through Android Messages, the default messaging app that comes installed on most Android devices.
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The first daughter and top adviser to the president has begun selling her women's wear collection on the her website for the first time, according to Bloomberg, in attempt to reverse declining sales.The website, previously a lifestyle blog, started flogging her clothing brand this week with a 15 percent discount just over a year since companies including Nordstrom, Burlington Coat Factory and Belk stopped selling the line, amid a political backlash.Nordstrom dropped Ivanka Trump in February 2017, citing poor brand "performance" and waning sales.The retailer had also been the target of Grab Your Wallet, a campaign started by Shannon Coulter and Sue Atencio, two women who, in the wake of the Access Hollywood tape, announced a boycott on any company carrying Trump products.Coulter and Atencio declared victory when Nordstrom announced it would no longer buy from Ivanka Trump.Not surprisingly, the ever-combative president was not happy and sprung to the paternal defence of his 36 year-old daughter.
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Tech Mahindra has announced a number of new investments into the UK, indicating the technology partnership signed between the UK and India recently was perhaps more than a PR stunt for the Prime Minister.The UK government is in need of friends right now, and India is looking like it could be our new trading chum.As part of the announcement, Tech Mahindra has set up a new research lab, ‘Makers Lab’, at Adastral Park near Ipswich in collaboration with BT, has opened a new office in Salford, Greater Manchester and also plans to roll out an apprenticeship programme in the UK.“Innovation is the key to survival in the digital future,” said CP Gurnani, CEO and MD of Tech Mahindra.“The UK-India Innovation partnership draws from the best learning and skills of both developed and developing economies in shaping the digital future.We at Tech Mahindra are taking the philosophy of disruption by design to our client ecosystem, academia and people through our research arm Makers Lab in UK.”
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Britney back in 2001, in the video for her single ‘Don’t Let Me Be The Last To Know’.But of course, you didn’t need us to tell you that, right?This piece of fashion history was spotted by BuzzFeed’s Matt Stopers who is a self-proclaimed “former 1 Britney Spears fan”.Britney Spears literally still has the shorts from her Don't Let Me Be The Last To Know (gorgeous) video.Her insta today vs. the video in 2000.You can't bc your fav is NOT!
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Facebook is reportedly building a team to design its own semiconductorsFacebook is reportedly looking to wean itself off its dependency on chip giant Intel, with the creation of a team to design its own semiconductors.This is the speculation after Facebook placed a job posting on its corporate website, seeking a manager to build an “end-to-end SoC/ASIC, firmware and driver development organisation.”This would suggest that the social network is still in very early stages of the process, but the move would add to Facebook’s existing hardware expertise in the server environment.The news that Facebook is seeking to develop its own chips was reported by Bloomberg, which cited the job listings and people familiar with the matter.If true, it would mean Facebook has become the latest tech firm seeking to develop its own silicon.
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Comparison shopping websites won't use Chocolate Factory fixCalls are mounting for the European Commission to issue a non-compliance notice against Google over attempts to address complaints about its market dominance.In June the commission found Google had abused its general search supremacy to illegally favour its own service over rival comparison shopping websites – landing it a €2.42bn (£2.1bn) fine.Google is appealing against the ruling and said the concessions it has made meet the commission's requirements for equal treatment.As a remedy, Google introduced an auction mechanism, allowing price comparison websites to bid for space in its "shopping box", which appears at the top of the results page when a user searches for a product.However, evidence submitted to the commission by one of the original complainants, Foundem, has argued that this does not comply with the commission's prescribed equal treatment remedy.
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