The world is still celebrating the historic landing of China’s Chang’e-4 on the far side of the moon on January 3.Last month, China announced its plans to follow up with three more lunar missions, laying the groundwork for a lunar base.Colonizing the Moon, and beyond, has always being a human aspiration.Technological advancements, and the discovery of a considerable source of water close to the lunar poles, has made this idea even more appealing.If we focus on the technology currently available, China could start building a base on the Moon today.The first lunar base would likely be an unmanned facility run by automated robotics – similar to Amazon warehouses – to ensure the necessary infrastructures and support systems are fully operational before people arrive.
BOSTON - A combination of two drugs - one of them an immunotherapy agent - could become a new standard, first-line treatment for patients with metastatic kidney cancer, says an investigator from Dana-Farber Cancer Institute, reporting results from a phase 3 clinical trial."Patients receiving the drug combination also had a higher response rate - meaning their tumors shrank - than the sunitinib-only group," said Toni K. Choueiri, MD, senior and co-corresponding author of the report on the JAVELIN Renal 101 trial in the New England Journal of Medicine and Director of the Lank Center for Genitourinary Oncology at Dana-Farber."This is certainly better than sunitinib -- hopefully this will lead to Food and Drug Administration approval soon," said Choueiri, The Jerome and Nancy Kohlberg Professor of Medicine at Harvard Medical SchoolWhile progression-free survival was improved with the combination treatment, additional follow-up is needed to show whether the two-drug therapy extends overall survival compared to the standard regimen.Immunotherapy drugs such as avelumab - which blocks an immune checkpoint called PD-L1 - work by activating "exhausted" immune T cells so they can more effectively attack cancer cells.The results from this study showed that the median progression-free survival (PFS) - the length of time before the cancer began to worsen - was 13.8 months in the combination group and 7.2 months in patients receiving only sunitinib.
A wide choice of assistants has risen over the past few years, including Google Assistant, Apple’s Siri, Amazon’s Alexa, and Microsoft’s Cortana.The last of the bunch, Cortana, has seen better days.Microsoft argues this will allow it to innovate on the feature independently, but we can’t help but wonder if it’s signally the truth about how successful the voice assistant has been.In subsequent years, Cortana moved to Android, iOS, and even Xbox to help increase its popularity, but even that still wasn’t enough.That changes the interpretation of those lofty millions.In 2019, a PC-based voice assistant just isn’t a strong enough proposition.
Top-line numbers appear to show times are good: U.S. digital advertising revenues rose 22 percent year over year to $26.2 billion in the third quarter of 2018, according to the latest numbers from the trade body, compiled by PwC, with total spend throughout the first three quarters of last year totaling $75.8 billion.However, pull back the curtain a little and a darker, more Darwinian plot line appears to be forming, with spend consolidating into fewer and fewer hands, resulting in consequences that reverberate far and wide.The numbers, based on interviews with the largest companies in the sector and then further modeled out, have Sue Hogan, svp, research and measurement at the IAB, describing 2018 as a “landmark year” for the sector.David Silverman, PwC, partner, U.S., went on to say, “It’s no surprise that advertisers are following their target customers to whatever screen they are on, and that screen is more likely to be a digital one.”However, with a separate study by eMarketer forecasting that Amazon, Facebook and Google will collectively rake in 63 cents of every U.S. ad dollar spent by 2020, it would appear the flow of ad dollars is flowing in ever fewer directions.Although it is hard to make a direct comparison and determine cause and effect as to the dynamics in the market, the multiple rounds of layoffs at high-profile premium media outlets, such as BuzzFeed, Gannett and Vice, are in stark contrast to the buoyant numbers posted by such platform providers.
New York Fashion Week seen quite a bit of change over the past decade.And then in January 2015, Mercedes-Benz, which had served as NYFW’s title sponsor for eight years, announced its departure.Later that same year, Fashion Week relocated yet again, moving to the downtown Manhattan location of Spring Studios—though several designers now choose to show their collections at other locations.The milestone anniversary of the two working together is being commemorated with a series of fashion illustrations featuring past Maybelline runway looks from artist Jeanette Getrost.Jeanette Getrost's illustrations, created in honor of Maybelline's 10-year anniversary with NYFW.Maybelline’s cooperation with NYFW has changed over that decade—keep in mind, Instagram did not yet exist in 2009.
WPP’s Ogilvy has gone through yet another round of executive and organizational changes as part of its two-plus-year restructuring.In an internal memo sent to all staff last night with the subject line “Next Phase Next Chapter,” global CEO John Seifert confirmed a series of promotions and departures as he seemingly finalized the makeup of his new leadership team."Now may be a moment to move beyond 'Next Chapter' as a banner headline of our collective transformation, and simply accept the reality that change is perpetual."John Seifert, global CEO, Ogilvy“I am incredibly proud of our progress over the past three years as we embarked on the most comprehensive transformation agenda in the company’s 70-year history,” Seifert wrote, in reference to the reorganization that began in January 2017.“Now may be a moment to move beyond ‘Next Chapter’ as a banner headline of our collective transformation, and simply accept the reality that change is perpetual … and that we will always be pursuing, in big and small ways, a shared agenda to better ourselves and Ogilvy in the face of all that challenges and inspires us.”
(In case you missed it because no one ever, mentions it on the show, this season's lead is a VIRGIN.)A promo for season 23 shows the former football linebacker stomping toward a fence in the dark and declaring "I'm f-cking done," before hopping over it with the ease of someone who's definitely not a fence-jumping virgin.Dramatic music plays, the women contestants scream and host Chris Harrison drops a "holy s**t," looking into the camera with what looks to be a knowing Chris Harrison smirk.Could this actually be the "most dramatic season ever" ABC has promised so many times?It's the kind of moment reality TV was born for, one that's given viewers of the long-running dating show something to look forward to in an otherwise hum-drum season largely characterized by make-out sessions -- and a requisite cat fight here and there."At this point, Bachelor Nation is WAY more excited to see Colton jump a DAMN FENCE than lose his virginity," one fan tweeted.
To outsiders, President Trump’s brazen speech and unconventional style may make him seem like an outlier, the sum of leftover parts assembled by a pissed-off populace.But for one group of researchers, Trump’s idiosyncrasies aren’t so much a departure from societal norms as they are a continuation of a trend dating back more than a century.As a paper published this week in the Proceedings of the National Academy of Sciences explains, Trump is actually the culmination of a century-plus long trend in Presidential communication.Researchers came to this conclusion by studying campaign speeches and those that followed, relying on text analysis to measure Trump’s (and other world leaders) thinking, as made apparent by the things he says.They first analyzed prior studies, including one that looked over the college admissions essays of incoming students.Some political figures communicate their ideas formally and focus on ideas and concepts (high analytic) while others communicate their ideas more informally and focus on people and actions (low analytic).
While we haven’t been able to verify the news at this time, if true, the move comes shortly after Chinese maker Oppo Digital decided to do the same thing last year.The news is both curious and a little worrying for what it might say about the state of the still-young 4K Ultra HD Blu-ray disc market.After all, if Samsung can’t make money in a consumer tech area like home theater — which it has been dominating along with LG for years — how healthy could that market be?And yet, many of the available stats tell the opposite story: Sales of Ultra HD Blu-ray discs are on the rise and support for the format from major Hollywood studios hasn’t ebbed at all, even though not every new movie is getting released as an Ultra HD Blu-ray.Sales of 4K Ultra HD Blu-ray discs, “soared 68 percent” in the third quarter of 2018, from the same quarter in 2017, according to a report by Variety, which cited these numbers from DEG: The Digital Entertainment Group.The report goes on to cite other positive-sounding stats, like this one: “4K UHD discs already account for almost one in 10 new release discs sold in the U.S,” according to Eddie Cunningham, president of Universal Pictures Home Entertainment, and: “[UHD] Product sales are up 87 percent in comparison to the first three quarters of last year,” said Bob Buchi, president, worldwide, Paramount Home Media Distribution.
Poor grinders mistreat whole beans, pulverizing them inconsistently.That in turn leads to uneven coffee extraction, and ultimately, bad joe.Avoid this scenario by getting a grinder that delivers the goods.Yes, this list starts at $99, but that's because I tested all of these models personally, and just didn't like the results from the cheaper batch.I'll follow up to see if any other bargain models are worth the trade-off in the future.It can grind fine enough for espresso in a pinch.
Indonesian technology and financial services Finmas has launched its standalone mobile app.It’s designed to provide easy access to affordable and secure credit for underserved consumers as well as micro, small and medium-sized enterprises across Indonesia that need access to reliable and trusted financing options.The peer-to-peer lending platform is a collaborative venture between Hong Kong-based financial services startup Oriente and Indonesian conglomerate Sinar Mas.Finmas launched the beta of its mobile app a few months ago.The app “enables consumers to apply for a cash loan whenever they need access to credit for tuition fees, household expenses, specific consumer goods, emergencies, or to start and grow their small businesses,” the company said in a statement.Finmas targets people who have little to no access to traditional financial services like bank accounts as well as credit rating and history.
Tencent on Thursday released on its official gaming WeChat account a list of 12 rules for live-streaming platforms and streamers, forbidding a number of behaviors in all live-stream shows that involve its games.The new rules come just two weeks after the release of China’s first official standards for live-streaming organizations, issued by authorities in the central Chinese city of Wuhan, which cracked down on underage streamers and stipulated how female streamers should dress.Those standards followed a set of guidelines by the China Netcasting Services Association (CNSA) also released last month, which listed a total of 100 categories of non-compliant types of content.While the 12 Tencent rules included broad articles pertaining to speech or behavior that go against national policies, social stability, and personal privacy, most of them relate specifically to the gaming side of live-streaming.According to one of the Tencent rules, any action that damages user experience and the brand of Tencent’s games is forbidden.Another article in the rules prohibits individual streamers from posing as representatives of live-streaming platforms or Tencent Games in order to spread false information.
Last week, an alt-rock mystery puzzled the music press.Almost 25 years after its release, the Dinosaur Jr. song “Over Your Shoulder” appeared at number 18 on Japan’s Hot 100 chart, beating out major new releases like Ariana Grande’s “7 Rings.”The fuzzy, mournful closer to Dinosaur Jr.’s 1994 album Without a Sound, “Over Your Shoulder” is an unlikely candidate for a hit single.Stranger still, the track rocketed up Japan’s charts thanks to over eight million video plays—earning the country’s top spot for video streams—despite no YouTube upload of the song having anywhere close to that many views.Well, some of us now know why, but it doesn’t make the incident—which involves Japanese bad boys, reality TV piracy, and renegade algorithms—any less strange.In the case of “Over Your Shoulder,” the only obvious connection between it and Japan was “Gachinko Fight Club,” a recurring segment on a variety show called Gachinko!
Google Duo is one of the best and simplest apps to initiate video calls from your smartphone.On Friday, in a post on OnePlus Forums, the company announced that with the upcoming OxygenOS update, Google Duo will become the native video calling app.The integration of the app comes as a result of a research study conducted by OnePlus back in 2018.The survey was conducted with OnePlus users across India on video calling wherein Google Duo ranked the highest in video call quality.The app as a native function has been integrated deeply into OxygenOS in functions such as Call logs, Contacts, Dial pad and Messaging.Stable OxygenOS updates for OnePlus 6T, 6, 5T and 5
Airbus has announced it will stop making the A380, the world’s largest passenger plane.The final one will roll off the production line in 2021.Distinctive for its double-decker design and sheer enormity, the plane has proved popular with those who fly on it, but sadly not so popular with airlines that consider it pricey and now prefer smaller, more efficient aircraft built by both Airbus and Boeing.The European aviation giant still has orders to fulfill, but not enough to justify long-term production.The A380 has a wingspan of 80 meters (262 feet) and is 73 meters (239 feet) long.Depending on how an airline configures it, the aircraft can carry as many as 850 passengers, though most carriers fit it with a mixture of seat types, bringing the number down to just over 500.
When you visit the website "This Person Does Not Exist" you will likely see a face smiling back at you.Seems innocent enough -- until you realize the face is not actually real, but generated by a neural network algorithm.That person is not real.The website's neural network algorithm codes a "facial image from scratch from a 512 dimensional vector", according to Phillip Wang, who created and posted about it in a Facebook group on Feb. 12.Wang suggested he created the site to "raise awareness for what a talented group of researchers made at Nvidia over the course of 2 years," according to a post in Hacker News.The technology is based on a state of the art Nvidia-designed AI known as StyleGAN -- a neural network that can separate aspects of an image to learn and generate new images.
Ride-hailing giant Go-Jek is looking for an advisor to assist with fundraising efforts as it expands in Southeast Asia, people with knowledge of the matter said.The Indonesia-based company has asked investment banks to pitch for a role in its ongoing series F round.The startup may look to raise up to US$2 billion in extra funds from investors, the sources said.Go-Jek has already raked in a little over US$1 billion in the round’s first close, led by existing investors Google, JD, and Tencent.Last month, rival Grab said that it raised US$3 billion in 2018 as part of its series H round.
Chinese high school students create daring sex education game, earning positive reviews on Steam – South China Morning PostWhat happened: Seven teenagers from Shanghai released an indie game on US platform Steam that tackles sticky sex-related issues.Without showcasing explicit content, Self-Reliance lets players take on scenarios such as potential unprotected sex and sexual assault.Despite being an amateur effort, the game has garnered “very positive” feedback from a large majority of reviewers thanks to its content and plot.Why it’s important: The game fills a gap in official education; for years, many public schools lacked formal sex education curriculum, although that may be changing.Besides offering a fun alternative, Self-Reliance’s appearance on Steam reflects the platform’s popularity in China.
Rival tech giants like Google and Facebook aren’t the only companies abusing Apple’s enterprise certifications to distribute unapproved apps in the Apple App Store on iOS, according to reports from Reuters and TechCrunch.Apple revokes Facebook’s developer certificate over data-snooping app—Google could be nextApple’s Enterprise Developer Program is intended to facilitate distribution of apps across devices internally within corporations, governments, and other organizations.But the Reuters report describes the use of enterprise certificates to distribute pirated versions of popular iOS software like Minecraft, Spotify, and Pokémon Go.The distributors impersonate legitimate businesses to gain access to Apple’s enterprise certification program and tools.They also offer both free versions of their services as well as cheap annual subscriptions that are priced at a point the legitimate services from which they steal could never viably match.
An unopened copy of Super Mario Bros. for the Nintendo Entertainment System (NES) sold for more than $100,000.The cartridge was an 1985 sticker-sealed reprint that was only available in the New York and LA to test-launch the NES.The game was sold through Heritage Auctions on Feb. 6 for $100,105 to a group of collectors.The game's box has a near-mint rating of 9.4 by Wata Games a website dedicated to rating collectible video games.The sticker has a seal rating of A++, which adds a great deal of value to the game."In terms of rarity, popularity, and relevance to collectors, this game has it all," said Wata Games President Deniz Kahn.