How much does Ledisof cost? Where to buy ledisof?

Description of the drug Ledisof

• Ledisof is a drug containing active ingredients Sofosbuvir 400mg and Ledipasvir 90mg used to treat hepatitis C genotypes 1a, 1b, 4,5,6 according to the MOH protocol.
• Ledisof is imported genuine from Hetero India and distributed into Vietnam market.
  Depending on the liver condition, Ledisof drug will be completely cured with 3 or 6 months of treatment.
• For patients with decompensated cirrhosis Ledisof in combination with Ribavin treatment from 3 to 6 months.

Mechanism of action

• Ledisof is a fixed dose combination (FDC) of ledipasvir and sofosbuvir, which are antiviral drugs that act directly against hepatitis C virus (HCV).
• Ledipasvir is an inhibitor of the HCV NS5A protein, necessary for viral replication. Sofosbuvir is an HCV NS5B-dependent RNA polymerase inhibitor, necessary for viral replication.
• Sofosbuvir is a nucleotide precursor that undergoes intracellular metabolism to form pharmacologically active uridine triphosphate (GS-461203), which can be combined with NS5B polymerase into RNA.

Electrophysiology of the heart

• Thorough research on QT has been conducted on ledipasvir and sofosbuvir. The effect of ledipasvir 120 mg twice daily (2.67 times the maximum recommended dose); within 10 days for the QTc interval assessed at random; multiple doses, placebo and active control (moxifloxacin 400 mg); three times, throughout the QT Test in 59 healthy subjects.
• At a dose of 120 mg twice daily (2.67 times the maximum recommended dose), ledipasvir did not extend the QTc interval to any clinically appropriate level. The effect of sofosbuvir 400 mg (maximum recommended dose) and 1,200 mg (triple the maximum recommended dose).
• For QTc intervals assessed in a randomized, single dose, placebo, and activity control (moxifloxacin 400 mg), four phases, cross-over meticulously tested in 59 healthy subjects. At a dose three times the maximum recommended dose.

How is this medicine Ledisof best taken?

• Use this medication as required by your doctor. Read all the information provided to you. Follow all instructions closely.
• Take this medication at the same time of day.
• Bring with or without food.
• If you have trouble swallowing, talk to your doctor.
• Keep taking this medicine as you were told by your doctor or other health care provider, even if you feel fine.
• It is important that you do not miss or skip a dose of this medication during treatment.

What do I do if I miss a dose?

• Miss a dose as soon as you think about it.
• If you do not think about the missed dose until the next day, skip the missed dose and return to your normal time.
• Do not exceed 1 dose of this medication on the same day.
• If you are not sure what to do if you miss a dose, call your doctor.

Warning about drugs Ledisof

• Alcohol: It is not known whether it is safe to use alcohol with Ledifos 90mg / 400mg Tablet. Please consult your physician.
• Pregnancy: Ledifos 90mg / 400mg Tablet is generally considered safe when used during pregnancy. Animal studies have shown low or no effect on the developing baby; However, there are limited studies in humans.
• Breast-feeding: Ledifos 90mg / 400mg Tablet may be safe to use during breastfeeding. Limited human data indicates that the drug does not present any significant risk to the baby.
• Driving control: Ledifos 90mg / 400mg Tablet may cause side effects that may affect your ability to drive. When taken together with other medicines to treat hepatitis c infection, it can cause dizziness, blurred vision and this may affect your ability to drive.
• Kidney: Ledifos 90mg / 400mg should be used with caution in patients with severe kidney disease. You may need to adjust the dose of Ledifos 90mg / 400mg Tablet. Please consult your physician.
• Liver: Ledifos 90mg / 400mg Tablet is safe to use in patients with liver disease. Ledifos 90mg / 400mg Tablet should not be adjusted.

Storage of Ledipasvir

• Store Ledipasvir at room temperature, 68 ° F to 77 ° F (20 ° C to 25 ° C).
  Keep the medication in the container it came in and hold the container tightly.
• Do not use the medicine if the original seal on the container door is broken or missing.
• Throw away medications that are no longer needed or have expired (expired). Follow FDA guidelines on how to dispose of unused medicines safely.
• Keep medicines and all medicines out of the reach of children.

See more general knowledge information

• Thuoc ledisof dieu tri viem gan C – Gia thuoc ledisof https://nhathuocgan.com/thuoc-ledisof-dieu-tri-viem-gan-c/
• Thuoc Ledisof dong thuoc dac tri viem gan C hieu qua dieutriung https://dieutriung.org/thuoc-ledisof-tri-viem-gan-c/
• Thuoc Ledisof hoat chat Ledipasvir 90mg va Sofosbuvir 400 mg https://nhathuocgan.blogspot.com/2019/12/thuoc-ledisof-hoat-chat-ledipasvir-sofosbuvir.html