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Epidermolysis Bullosa Therapeutics Depends On Severity of the Disease and Can Include Simple Topical Medications and Surgery

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Ajinkya
Epidermolysis Bullosa Therapeutics Depends On Severity of the Disease and Can Include Simple Topical Medications and Surgery

Epidermolysis bullosa is a rare genetic autoimmune disease. The disease is characterized by thickening of the skin layers. This thickened skin causes the skin to die and eventually ulcerates. This condition occurs in young women during their menstrual cycles. This complication of this disease is more common in young women.

The disease can be successfully treated. Epidermolysis bullosa therapeutics mostly depends on the severity of the disease and can include simple topical medications and surgery. Sometimes, patients require more than one treatment to completely cure the skin condition. For instance, if a patient suffers from severe bullous epidermolysis, he may need more than one type of medication, such as oral medications and skin grafts.

Epidermolysis bullosa therapeutics involves multiple treatments in order to achieve remission. However, relapse is common after any form of treatment is discontinued. There is currently no specific therapy that can prevent the recurrence of this condition. Most patients choose to undergo an aggressive plan of treatment, including frequent blood transfusions, vitamin D, chemotherapy, immunosuppressant drugs, topical antioxidants and surgery. Unfortunately, all of these treatments do not provide permanent relief and most patients are still affected by this disease. There is presently no cure for this illness.

Cell-based epidermolysis bullosa therapeutics can successfully treat this disease. Cell-based therapies include bone marrow transplantation and bone marrow accumulation. Bone marrow is the part of the bone that contains stem cells. These stem cells can be obtained from the bone marrow of the donor or the patient's own bone marrow.

During the first step of cell-based epidermolysis bullosa therapeutics, the bone is harvested from the patient. The bone is then divided into approximately 200 small pieces and put back into the bone marrow for collection. This collection is done under local anesthesia. A needle with a glass needle at the end is inserted into the bone to collect the stem cells. Patients usually undergo this therapy once or twice. If there are recurrent cases of this disease, more transplants may be required. For patients who have had this disease for more than five years, additional transplants might be required.

Surgery is the final option in epidermolysis bullosa therapeutics. Epidermolysis bullosa surgery is usually performed on an outpatient basis. Most people who undergo surgery have their skin removed from areas where the hair is dense. The surgery involves an incision of the skin, fat transfer, wound dressing change and scarification. The surgery may also involve minor removal of some body tissues for evaluation and possible graft replacement.

Before surgery, it is best for the patient to undergo chemotherapy or radiation epidermolysis bullosa therapeutics. These drugs help in slowing down the disease process and also in preventing further skin damage. Surgery is performed only after these other drugs are ineffective. A high success rate of patients following this surgical procedure has been reported. However, this disease usually recurs within three years.

 

Read More @ https://www.linkedin.com/pulse/epidermolysis-bullosa-therapeutics-depends-severity-disease-ajinkya-k/

 

 

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