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Kidney Cancer Drugs have Improved Over the Years with Typical Application in Combination with Chemotherapy and Targeted Therapy

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Ajinkya
Kidney Cancer Drugs have Improved Over the Years with Typical Application in Combination with Chemotherapy and Targeted Therapy

Kidney cancer is one of the deadliest types of cancer, and a recent study has confirmed its rapid spread across the globe. More people are diagnosed with this cancer every year than breast or lung cancer. Based on these observations, combination chemotherapy with targeted therapy plus chemotherapy has been developed as the basis of the new targeted kidney cancer drugs. These include both systemic and local approaches. Systemic approaches include systemic dimercaprol and cyclophosphamide and this combination allows the systemic administration of two strong anti-cancer agents, doxorubicin and methotrexate.

Local approaches include rituximab, carboplatin, and doxorubicin localized to the affected area. This combination allows the administration of a single strong drug that controls the tumor growth as well as the protein deposition and the metabolic activity of the tumor cells. Targeted therapy combines several previously used kidney cancer drugs including doxorubicin, methotrexate, and cytotoxic agents. The most common use of targeted therapy is to treat the tumors and renal tubule. Toxicity is reduced in such cases as the target is only the cancer cells. Systemic toxicity is very high in kidney cancer drugs and therefore, local or primary targeted therapy is preferred for overall success in treatment.

Chemotherapy is the standard treatment for all forms of kidney cancer. It can be used alone or in combination with other treatments. It can be administered in a variety of ways such as injection, catheterization, and oral ingestion. Chemotherapy drugs are generally administered on an outpatient basis under general anesthesia for short periods of time. There are four main categories of drugs used in the treatment of cancer of the renal pelvis and urinary tract nonsteroidal, hormonal, stereoscopic, and selective serotonin reuptake inhibitors (SSRIs). Most people get kidney cancer drugs through prescription. Hormone medications can either be given as monoclonal or conjugated. Non-hormonal agents are usually given once a year as maintenance therapy. If hormonal therapy is necessary, usually it is given after the initiation of hormonal therapy.

Some cases of advanced kidney cancer are treated with surgery followed by chemotherapy and radiation therapy. However, surgery alone may not be effective in treating advanced cases of cancer. The side effects of surgery include infection, bleeding, and temporary or permanent disability of the organ being operated on. Although chemotherapy drugs have fewer side effects than surgery, it is more difficult to treat side effects than it is to cure them. Some types of chemotherapeutic drugs have been approved by the FDA.

The prognosis for patients with advanced cancer of the kidney varies depending on the type of cancer, the age at the time of diagnosis, the stage of the disease, the extent of tumor growth, and the response to treatments offered. Sometimes, if cancer has spread to the lungs or heart, there is a high risk for death. This is why patients who have both cancer and kidney disease are given extra attention to prepare for possible kidney failure. Chemotherapy may be administered after surgery and may also be used to extend the life expectancy of the patient.

 

Read More @ https://www.linkedin.com/pulse/kidney-cancer-drugs-have-improved-over-years-typical-application-k/

 

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