Cerebrolysin is a neurometabolic stimulator based on neuropeptides (20 percent) and amino acids (80 percent) isolated from pig brain tissue. It was developed in 1949 by Gerhart Harrer, an Austrian professor, and approved on August 1, 1954.
Used as a treatment for:
- Strokes and complications associated with strokes
- Depression, anxiety, and other brain diseases
- Alzheimer's disease and other types of dementia
- Traumatic brain injury and spinal cord injuries
- ADHD in children
Country of Manufacture: Austria
Contraindications
– individual intolerance to the drug
– acute renal failure
– status epilepticus
Side effects
– fever, sensation of heat (with rapid intravenous infusion)
Rarely:
– headache, dizziness
– loss of appetite, nausea, vomiting, dyspepsia, diarrhea, constipation
– allergic reactions: skin redness, itching and burning at the injection site
Mode of application
It is used only parenterally: in the form of intramuscular injections (up to 5 ml), and intravenous infusions (10-60 ml), it is recommended to enter only by slow intravenous infusions after dilution with the proposed standard solutions for infusion. The duration of the infusion is 15 to 60 minutes. Doses and duration of treatment depend on the nature and severity of the disease, as well as on the patient’s age. Perhaps the appointment of single doses, the value of which can reach 60 ml, but it is more preferable to conduct a course of treatment. The standard duration of treatment is 4 weeks (5 injections / infusions per week, preferably daily).
To increase the effectiveness of treatment, repeated courses can be carried out until positive treatment results are obtained. After the first course, the frequency of prescribing doses can be reduced to 2 or 3 times a week.
In Alzheimer’s disease, dementia syndrome of various origins: intravenous infusion of 20-30 ml in 100-200 ml of saline, for a course of treatment 20 infusions, 5 infusions per week (followed by a 2-day break) for 28 days. If necessary, the course of treatment is repeated after 3-6 months.
Acute conditions (ischemic stroke, acute and rehabilitation phase): in severe ischemic stroke, Cerebrolysin is prescribed as drip infusion in a daily dose of 20-30 ml in 100-250 ml of saline for 60-90 minutes. The duration of the course is 10-25 days.
For moderate ischemic stroke, the daily dose is 10-20 ml in 100-250 ml of saline for 60-90 minutes. The duration of the course of treatment is 10-25 days.
In the recovery period – 10 ml per day, intravenously, for 20-30 days.
Traumatic brain and spinal cord injury: intravenous infusion of 10-20 ml for 10-20 days. In the recovery period, intravenously, 5-10 ml, for 20-30 days.
With psychoorganic syndrome and endogenous depression: intravenous infusion of 5-30 ml, 5 infusions per week (followed by a 2-day break) for 20-25 days. If necessary, repeat the course of treatment after 6 months.
In neuropediatric practice (mental retardation in children, attention deficit disorders in children): the average daily dose is 0.1 – 0.2 ml / kg intramuscularly, daily. The duration of the course of treatment is 30 days, with a repetition of the course 2-3 times a year.
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