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Sample preparation is a crucial process which can greatly impact the accuracy of research and are responsible for the success of downstream applications

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Sample preparation is a crucial process which can greatly impact the accuracy of research and are responsible for the success of downstream applications

Increasing interest in developing quick, cost-effective, and environmentally friendly sample preparation techniques, lead to develop new methods which will eventually minimize the extraction steps, reduce solvent consumption, and thereby automate the sample preparation system. Sample preparation is necessary to isolate the desired or targeted components from complex matrices, which most analytical instruments cannot handle the matrix directly.

Sample preparation is a crucial process which can greatly impact the accuracy of research and are responsible for the success of downstream applications, such as nucleic acid or protein isolation and purification, pipetting, and other liquid-handling requirements. Current sample preparation trend includes miniaturization, automation, high-throughput performance, ability of new sample preparation instruments to combine with existing analytical instruments and reduction in solvent volume and time.

Before Sample Preparation can begin, it is essential to ensure that all the equipment, tools, and materials are ready. The most important equipment used in analytical chromatography is the chromatography machine. The machine is responsible for both the qualitative and quantitative analysis of the samples, with the assistance of a combination of mechanical and chemical processes. There are several types of chromatography machines and each one is designed to give the best results at the lowest possible cost.

Moreover, continuous innovation in sample preparation and integration of new technology, will further drive the sample preparation market. For instance, integration of QuEChERS method in solid phase extraction allows simple and streamline sample preparation system for analysis of various pharmaceutical and veterinary drugs. Automated sample preparation eliminates human error, low sample purity, and sample contamination, allowing consistent result at every time.

Samples should be prepared methodically and consistently, following the guidelines provided in the Method section. Methods for sample preparation can be based on established analytical methods, applied to the analytical data to derive quantitative data. Some methods have been developed specifically for the preparation of samples in oil extraction, precipitation, solid-phase gel studies, etc.

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