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Malaria Vaccines Provide Protection Against Mosquito-Borne Diseases

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Malaria Vaccines Provide Protection Against Mosquito-Borne Diseases

The development of a Malaria Vaccines is a complex and challenging process. The parasite that causes malaria has a complex life cycle, and it is able to evade the immune system by changing its surface proteins. This makes it difficult for the body to mount an effective immune response against the parasite.


One approach to developing a Malaria Vaccines is to target the proteins on the surface of the parasite that are responsible for evading the immune system. These proteins, known as variant surface antigens (VSAs), are highly variable, but some common features can be identified. Researchers have identified a number of VSAs that are shared among different strains of the parasite, and they are working to develop vaccines that target these common features.


Malaria is a deadly disease that kills over 400,000 people a year, mostly children. Mutating parasites and growing resistance to drugs and insecticides have stalled progress toward a malaria-free world. The World Health Organization has endorsed the first-ever malaria vaccine, RTS, S/AS01. It is the result of 30 years of research and development by GSK, PATH, and partners. 


Another type of Malaria Vaccine, called a pre-erythrocytic vaccine, targets the first stage of the parasite’s life cycle by intercepting sporozoites before they get to the liver. A third type of vaccine, called a transmission-blocking vaccine, prevents the formation of new gametes in an infected host. These are the reproductive cells of the parasite that can be ingested by a mosquito and initiate infection. 



Read More- http://latestcmiblogs.weebly.com/article/a-malaria-vaccine-is-used-to-prevent-malaria-and-is-administered-in-people-living-in-moderate-to-high-malaria-transmission-regions


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