Rheumatoid Arthritis (RA) is an autoimmune disorder that affects the joints and other parts of the body. The condition causes chronic inflammation, pain, and swelling, which can lead to joint damage and disability if left untreated. There is no cure for RA, but there are several treatment options available that can help manage symptoms and slow down the progression of the disease.
The goal of Rheumatoid Arthritis Treatment is to achieve remission, which means that the disease is no longer active and symptoms are under control. This can be achieved through a combination of medication, lifestyle changes, and supportive therapies.
Medications
The most commonly prescribed medications for RA are disease-modifying antirheumatic drugs (DMARDs). These drugs work by suppressing the immune system and reducing inflammation in the joints. There are several types of DMARDs, including:
Methotrexate: This is often the first-line Rheumatoid Arthritis Treatment. It works by blocking the action of an enzyme that is involved in the production of cells that cause inflammation. Methotrexate can take several weeks to start working, and it may cause side effects such as nausea, fatigue, and hair loss.
Biologic DMARDs: These drugs are designed to target specific parts of the immune system that are involved in the development of Rheumatoid Arthritis. They are typically used in combination with methotrexate or other DMARDs. Biologic DMARDs include drugs such as etanercept, adalimumab, and infliximab. These drugs are usually given by injection or infusion, and they may cause side effects such as injection site reactions, infections, and allergic reactions.
Janus kinase (JAK) inhibitors: These drugs work by blocking the action of a specific enzyme involved in the inflammatory process. They are taken orally and include drugs such as tofacitinib and baricitinib. JAK inhibitors may cause side effects such as infections, gastrointestinal problems, and changes in blood cell counts.
Corticosteroids: These drugs are potent anti-inflammatory medications that are used to reduce inflammation and pain in the joints. They are typically used for short periods of time due to their side effects, which can include weight gain, high blood pressure, and increased risk of infections.
Nonsteroidal anti-inflammatory drugs (NSAIDs): These drugs are used to relieve pain and reduce inflammation in the joints. They include drugs such as ibuprofen, naproxen, and aspirin. NSAIDs can cause side effects such as stomach ulcers, gastrointestinal bleeding, and kidney problems.
