The field of molecular biology has witnessed significant progress in recent years, thanks to the continuous advancements in technology. Digital PCR (dPCR) and Real-time PCR (quantitative PCR or qPCR) are two key techniques that have revolutionized the way we analyze nucleic acids. In this blog post, we'll explore the latest trends and developments in the Digital PCR and Real-time PCR market Share.
Digital PCR (dPCR)
Digital PCR is a groundbreaking technique that allows for the precise quantification of DNA or RNA molecules in a sample. Unlike traditional PCR methods, dPCR partitions a sample into thousands of tiny droplets or wells, where each contains a minute amount of nucleic acid. By counting the positive and negative partitions, researchers can determine the absolute quantity of the target molecule.
Recent Advancements in dPCR:
1. Ultra-sensitive Detection: The latest dPCR platforms offer ultra-sensitive detection capabilities, enabling researchers to detect rare mutations or low-abundance targets with high precision. This has profound implications in fields like cancer research and diagnostics.
2. Multiplexing: Multiplex dPCR allows the simultaneous detection of multiple targets in a single reaction, saving time and resources. This feature is especially valuable in infectious disease monitoring and genetic testing.
3. Integration with Next-Generation Sequencing (NGS): Combining dPCR with NGS technologies provides a comprehensive approach to studying genetic variation. Researchers can validate NGS results with high-confidence data from dPCR.
Real-time PCR (qPCR)
Real-time PCR, or quantitative PCR (qPCR), is another powerful tool in molecular biology. It measures the amplification of DNA during each cycle of the PCR process, providing quantitative data in real-time. This technique is widely used in gene expression analysis, pathogen detection, and genotyping.
Recent Advancements in qPCR:
1. Multiplexing and High-Throughput Systems: Modern qPCR instruments support multiplexing, allowing the quantification of multiple target genes in a single reaction. High-throughput qPCR systems are also available, which expedite large-scale gene expression studies.
2. Digital PCR Integration: Some qPCR platforms now offer dPCR capabilities, combining the advantages of both techniques. This integration enhances the accuracy and sensitivity of quantification.
3. Advanced Data Analysis: The development of sophisticated data analysis software has simplified the interpretation of qPCR results. Researchers can now perform more complex analyses, such as melting curve analysis and allelic discrimination, with ease.
Market Trends
The Digital PCR and Real-time PCR market continue to grow rapidly, driven by increasing demand from various sectors, including healthcare, biotechnology, and research. Key market trends include:
1. Diagnostic Applications: The adoption of dPCR and qPCR for diagnostic purposes, especially in the detection of infectious diseases and genetic disorders, is on the rise.
2. Pharmaceutical Research: These techniques are essential in drug development, helping researchers assess the efficacy and safety of new pharmaceutical compounds.
3. Environmental Monitoring: Environmental agencies employ dPCR and qPCR to monitor water quality, detect contaminants, and study microbial communities in various ecosystems.
4. Automation: Automation and robotics are becoming integral to both dPCR and qPCR workflows, improving efficiency and reducing human error.
Conclusion
Digital PCR and Real-time PCR technologies have transformed molecular biology research and diagnostics. With continuous innovation and integration of advanced features, these techniques are poised to play an even more significant role in understanding genetics, diagnosing diseases, and advancing scientific knowledge. As the market continues to evolve, staying informed about the latest developments is crucial for researchers and professionals in the field.
Read More….
Pharma Grade Magnesium Trisilicate Market
Non-alcoholic Steatohepatitis (NASH) Therapeutics and Diagnostics Market
Indefinite Volume Pipette Market
Postpartum Depression Drug Market
Real Time PCR (QPCR) Market OverviewGlobal Real Time PCR (qPCR) market is valued at US$ 4,154.9 Mn in 2018 and is expected to grow at a CAGR of 8.8% to reach US$ 8,890.5 Mn in 2030.
Limited supply of real time PCR (qPCR) testing kits in various countries is leading healthcare organizations to search for innovative testing solutions.
In real time PCR (qPCR) testing, RNA samples from a patients are utilized for testing through polymerase chain reaction (PCR) for understanding the presence of virus SARS-CoV-2.
Virus SARS-CoV-2 is responsible for COVID-19.Access Full Report Details and Order this Premium Report @ https://www.absolutemarketsinsights.com/reports/Real-Time-PCR-qPCR-Market-2019-2030-555Top Key Venders of Market:Some of the players operating in the Real Time PCR (qPCR) market are ABL SA Group, Agilent Technologies, Inc., Analytik Jena AG, BD, Bio-Rad Laboratories, Inc., F. Hoffmann-La Roche Ltd, Fluidigm Corporation, Lumex Instruments, Primerdesign Ltd, QIAGEN, Takara Bio Inc., Thermo Fisher Scientific, TOYOBO.inc., and Vela Diagnostics amongst others.Key Findings of the Report:The use of Real Time PCR (qPCR) (qPCR) for virus and bacterial analysis is expected to grow significantly over the forecast period.
The increasing adoption of the method for testing with respect to coronavirus (COVID-19) is aiding the growth of the segment in the global market.The usage of Real Time PCR (qPCR) is observed to be at the highest in healthcare sector through hospitals and clinics across various regions.
The increasing number of cases for testing of coronavirus (COVID-19) across various regions is aiding the growth of the segment in the market.As far as geography is concerned, the market for Real Time PCR (qPCR) is expected to grow at a faster rate in the North America region.
According to the new market research report "Digital PCR and qPCR Market by Product (Instruments, Reagents & Consumables, Software & Services), Application (Clinical, Research, Forensic), End User (Hospitals & Diagnostic Centers, Pharma Biotech, CROs) - Global Forecast to 2025", published by MarketsandMarkets™, the dPCR and qPCR market is projected to reach USD 7.6 billion by 2025 from USD 4.9 billion in 2020, at a CAGR of 9.0% between 2020 and 2025.Browse in-depth TOC on "Digital PCR (dPCR) and Real-time PCR (qPCR) Market"253 – Tables41 – Figures316 – PagesDownload PDF Brochure: https://www.marketsandmarkets.com/pdfdownloadNew.asp?id=174151204 The Factors such as the rising incidence of target infectious diseases and genetic disorders; technological advancements in PCR technologies; increasing investments, funds, and grants; increasing use of biomarker profiling for disease diagnostics; and successful completion of the Human Genome Project are driving the growth of this market.
The qPCR reagents and consumables segment is expected to command the largest share of the qPCR products & services market in 2020, owing to the factors such as the expanding applications of qPCR (owing to its technological benefits over traditional PCR, such as real-time analysis and reduced analysis time), growing private-public funding for life science research, and the rising number of probe-based multiplex genetic analysis procedures (that require the analysis of low-volume gene samples).Clinical application segment accounted for the largest share of qPCR marketBased on application, the market is categorized into clinical applications (Infectious Disease Testing, Oncology Testing, Blood Screening, Transplant Diagnostics and Other Clinical Applications), research applications and forensic applications.
The key factors driving the market growth of cclinical applications segment include the growing usage of qPCR in disease diagnosis, rising incidence of infectious and genetic diseases, and growing public emphasis on early & effective disease diagnosis & treatment.The hospitals and diagnostic centers is the largest and fastest gowing end user segment of the qPCR marketBased on end users, the dPCR market is segmented into research laboratories and academic institutes, pharmaceutical and biotechnology companies, hospitals and diagnostic centers, clinical research organizations (CROs), and forensic laboratories.
This can be attributed to the increasing market availability of qPCR reagents for clinical diagnostic applications, ongoing expansion of healthcare infrastructure across emerging countries, high prevalence of target diseases, and growing awareness among end users related to the benefits offered by qPCR for clinical diagnosis.North America accounted for the largest share of the dPCR marketNorth America accounted for the largest share of the dPCR and qPCR market, followed by Europe in 2019.
The large share of the North American regional segment can be attributed to the increased adoption of innovative and novel genomic analysis products (including advanced qPCR and dPCR products), availability of R funding for genomic research (coupled with the robust research infrastructure in the region), expanding use of PCR techniques in clinical diagnostics & forensics, and early commercialization of qPCR/dPCR products compared to other regions.Request Sample Pages: https://www.marketsandmarkets.com/requestsampleNew.asp?id=174151204 The prominent players operating in the dPCR and qPCR market are Thermo Fisher Scientific (US), Bio-Rad Laboratories Inc. (US), and F. Hoffmann-La Roche, Ltd. (Switzerland).About MarketsandMarkets™MarketsandMarkets™ provides quantified B2B research on 30,000 high growth niche opportunities/threats which will impact 70% to 80% of worldwide companies' revenues.
Currently servicing 7500 customers worldwide including 80% of global Fortune 1000 companies as clients.
