The Global Ribonucleic Acid (RNA) Markers Market is estimated to be valued at US$ 226.6 Mn in 2023 and is expected to exhibit a CAGR of 8.7% over the forecast period 2023 to 2030, as highlighted in a new report published by Coherent Market Insights.
Market Overview:
RNA markers help detect diseases through the analysis of RNA levels in the body. They are useful biomarkers of diseases since RNA levels can indicate abnormal gene expression associated with various disease conditions. Advances in RNA extraction technologies and sequencing have expanded the utility of RNA markers in clinical diagnostics.
Market key trends:
One of the key trends in the RNA markers market is the increasing focus on non-coding RNAs (ncRNAs) as biomarkers. While most genetic research has focused on protein-coding genes, it is now known that ncRNAs, such as microRNAs and long non-coding RNAs, play important regulatory roles in various biological processes. Several studies have identified specific ncRNAs that show potential as clinically useful biomarkers for cancers and other diseases. For example, certain microRNAs have shown promise as biomarkers for prostate cancer, melanoma, and Alzheimer’s disease. The identification of more ncRNAs linked to human diseases is expected to boost the development of ncRNA-based biomarkers.
Segment Analysis
The global RNA markers market is segmented based on analysis technique, product type, and application. Under analysis technique, quantitative polymerase chain reaction (qPCR) dominates the market as it offers high sensitivity and specificity for RNA quantification. qPCR is the most widely used technique for the detection and quantification of RNA markers.
Key Takeaways
The Global Ribonucleic Acid (Rna) Markers Market Analysis is expected to witness high growth, exhibiting CAGR of 8.7% over the forecast period, due to increasing prevalence of cancer and other chronic diseases. Regional analysis - North America dominates the global RNA markers market owing to growing R&D investment and technological advancements in the region. The Asia Pacific region is expected to witness fastest growth over the forecast period due to rising healthcare expenditure.
Key players operating in the Ribonucleic Acid (RNA) Markers Market are Agilent Technologies, Inc., Oxford Gene Technology IP Limited, PerkinElmer Inc., Eurofins Scientific, F. Hoffmann-La Roche Ltd, NextGen Life Sciences Private Limited, bioMérieux SA, New England Biolabs, Promega Corporation, Merck KGaA, Takara Bio Inc., Abnova Corporation, Thermo Fisher Scientific Inc., QIAGEN, Bio-Rad Laboratories, Inc., Lonza, CardioNet, ZOLL Medical Corporation and Hill-Rom Services, Inc.
The COVID-19 pandemic has caused more than 600,000 deaths in the United States since the start of 2020 and more than 4 million globally.
RNA is a type of genetic code that can be translated into proteins that allow the virus to replicate.
During its RNA duplication, the virus would typically have a distinct chemical genetic signature -; a string of molecules, or bases, that appends to one end of SARS-CoV-2's RNA backbone.This chemical signature would normally be recognizable by the body and produce an immune response, but the virus has a special way of hiding the extra molecules and sneaking into the body undetected.
The research team used the resources of the Advanced Photon Source (APS), a DOE Office of Science User Facility at Argonne, to test a new treatment option that may foil this mechanism.The research was led by Andrzej Joachimiak of Argonne and the University of Chicago, with Argonne protein crystallographer Youngchang Kim and University of Chicago structural biologist Natalia Maltseva and their colleagues.
Joachimiak is the director of the Structural Biology Center (SBC) at the APS, and the research team used the high-powered X-ray beams generated there to study one of the virus's proteins, called Nsp15.This protein acts like a molecular scissors, cutting regions of the virus that are involved in its ability to make copies of itself.
As more and more of those strings of molecules -; made up of uridine, one of the main components of nucleic acid -; are produced, the Nsp15 molecule removes them, essentially giving the virus the haircut it needs to pass undetected undercover.
