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PD-1 and PD-L1 Inhibitor Market is Estimated to Witness High Growth Owing to Opportunity for Cancer Treatment

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Purvaja
PD-1 and PD-L1 Inhibitor Market is Estimated to Witness High Growth Owing to Opportunity for Cancer Treatment

PD-1 and PD-L1 inhibitors are a class of drugs used for cancer treatment. These drugs help boost the immune system's ability to recognize and destroy tumor cells by blocking interaction between programmed cell death protein 1 (PD-1) and its ligand PD-L1. The need for cancer treatment has been rising significantly owing to increasing prevalence of various cancer types globally. PD-1 and PD-L1 inhibitors offer promising alternatives to conventional cancer treatment options by improving response rates and clinical outcomes. The global PD-1 and PD-L1 Inhibitor Market is estimated to be valued at US$ 39.83 Bn in 2023 and is expected to exhibit a CAGR of 19.% over the forecast period 2023 to 2030, as highlighted in a new report published by Coherent Market Insights.

Market Opportunity:

The rising incidence of cancer presents a major market opportunity for PD-1 and PD-L1 inhibitors. According to the World Health Organization (WHO), cancer burden has risen to 18.1 million new cases and 9.6 million deaths in 2018 worldwide. The four major cancers namely lung, breast, colorectal and prostate cancers account for more than 40% of all cancer cases. With limited treatment options and high unmet needs, PD-1 and PD-L1 inhibitors are poised to gain traction in the global cancer treatment market, benefitting from their promising efficacy and improving survival rates in various tumor indications.

Porter's Analysis

Threat of new entrants: The PD-1 and PD-L1 Inhibitor Market faces moderate threat as significant capital requirements, specialized manufacturing capabilities, and regulations pose barriers for new firms. However, opportunities for biosimilars provide scope for new players.

Bargaining power of buyers: Individual drug consumers have low bargaining power due to rare conditions treated. However, large hospitals and insurance companies negotiating drug prices can influence drug makers.

Bargaining power of suppliers: Leading drug makers developing PD1/PD-L1 drugs enjoy strong bargaining power as switching costs and need for innovation dominates. Suppliers of raw materials have low-moderate power.

Threat of new substitutes: Alternate immunotherapies and targeted drugs pose threats, though PD1/PD-L1 based regimens have efficacy advantages and wider scope. Substitutes are developing slowly.

Competitive rivalry: Fierce as leading firms compete vigorously to develop newer indications and combinations. Price competition and partnerships to access markets also influence rivalry.

SWOT Analysis

Strengths: Efficacy in multiple cancers, innovation pipeline, large R&D investments, expanding insurance coverage.

Weaknesses: High drug costs, side effects, dependence on few large firms, scope for biosimilars.

Opportunities: Unmet needs in new cancer types, combinations with other therapies, patient assistance programs.

Threats: Patent expiries of top drugs, price regulations, stringent approvals for new indications.

Key Takeaways

The global PD-1 And PD-L1 Inhibitor Market Demand is expected to witness high growth supported by approvals for novel indications and combinations. The market size is projected to reach US$ 39.83 Bn in 2023 at a CAGR of 19%. North America currently dominates led by the US and is expected to retain its position owing to established care facilities, insurance coverage and proactive therapy adoption. Europe and Asia Pacific are emerging regions witnessing fast uptake of immunotherapies.

Regional analysis:

The Asia Pacific region is projected to witness the highest growth during the forecast period driven by increasing healthcare spends, rising cancer incidence, focus on biosimilar development by regional players and availability of generics. China, Japan and South Korea contribute significantly to the regional market owing to large population bases and improving access to innovative drugs.

Key players:

Key players operating in the PD-1 and PD-L1 Inhibitor market are Merck & Co., Inc., Bristol-Myers Squibb, F. Hoffmann-La Roche Ltd., AstraZeneca, Novartis, Regeneron Pharmaceuticals, Inc., ELI Lilly and Company, Boehringer Ingelheim, Astellas Pharma Inc. and Ono Pharmaceutical.

For more insights, Read- https://www.insightprobing.com/pd-1-and-pd-l1-inhibitor-market-demand-share-analysis/

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