Introduction
Allergies affect millions of people worldwide and cause unpleasant symptoms such as sneezing, itchy and watery eyes, runny nose, among others. Cetirizine hydrochloride is an effective prescription and over-the-counter antihistamine medication that provides relief from these allergy symptoms. In this article, we will discuss what cetirizine hydrochloride is, how it works, its benefits, side effects and more.
What is Cetirizine Hydrochloride?
Cetirizine hydrochloride, commonly known by the brand name Zyrtec, is a second-generation prescription and non-prescription antihistamine. It is classified as a piperazine compound and works by blocking the H1 receptor sites where histamine is attached and causes allergic symptoms. Cetirizine was first approved for medical use in the United States in 1995 and is now available as a generic drug as well. It comes in tablet, capsule, syrup and injectable forms.
Mechanism of Action
When allergens like pollen, dust or animal dander enter the body of sensitized individuals, they trigger the release of histamine through immunoglobulin E (IgE) antibodies. Histamine then binds to H1 receptor sites in tissues and blood vessels, leading to allergy symptoms. Cetirizine works by competitively blocking these H1 receptor sites, thus preventing the binding and effects of histamine. This results in relief from symptoms like sneezing, itchy eyes and nose. As an antihistamine, cetirizine does not cure or prevent allergies but reduces their severity during an allergic reaction.
Benefits of Cetirizine
Some key benefits of Cetirizine Hydrochloride include:
- Provides relief from common symptoms of hay fever, allergic rhinitis, hives and conjunctivitis like sneezing, itchy eyes, runny nose etc. within 30-60 minutes of use.
- Long-lasting 24 hour relief as it has a long plasma half-life. Only needs to be taken once daily.
- Non-drowsy formulation. Unlike older antihistamines, cetirizine is less likely to cause drowsiness.
- Safe for long-term daily use. Can be used as preventive medication during high pollen counts or allergy seasons.
- Available without a prescription for over-the-counter use. Prescription strength are also available for severe allergies.
- Well-tolerated formulation with less risk of anticholinergic side effects seen with some antihistamines.
- Can also help treat chronic idiopathic urticaria or hives of unknown cause along with anti-itch creams.
Dosage and Administration
Cetirizine is generally safe and well-tolerated by most people. The standard recommended dosage for adults and children over 6 years is one 10 mg tablet to be taken orally once a day, preferably in the morning. The 5 mg pediatric formulation is approved for children aged 6 to 11 years. It is usually taken with or without food but should be consumed with water. Tablets should be swallowed whole and not crushed or chewed.
Side Effects and Precautions
While cetirizine is considered relatively safe, some potential side effects may include:
- Dry mouth
- Fatigue
- Dizziness
- Headache
- Nausea
- Diarrhea
- Sleepiness (in a few cases)
Precautions should be taken if one has liver or kidney disease, pregnant/breastfeeding and interacts with certain medications like erythromycin, ketoconazole etc. Also, long-term usage is usually safe but discuss with a doctor for chronic conditions. As with any medication, cetirizine usage should be discussed with a health practitioner as per individual health history and requirements.
Cetirizine hydrochloride is an effective prescription and OTC antihistamine used worldwide to treat various allergy symptoms. With its long-lasting effects, non-drowsy profile and good safety record, it is considered as one of the preferred treatment options for allergic rhinitis, hives, and other acute and chronic allergic conditions. Cetirizine offers effective allergy relief without major side effects when taken as directed under medical guidance.
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Most importantly, this report also provides the latest significant strategies adopted by major players along with their market share.The research report also covers the comprehensive profiles of the key players in the market and an in-depth view of the competitive landscape worldwide.
The major players in the cetirizine otc market include J & J, Major(R) Pharmaceuticals, Sanofi, APOTEX, Teva, Pl Developments, Perrigo, Mckesson, CVS Pharmacy, Perrigo, Novel Laboratories.
This section includes a holistic view of the competitive landscape that includes various strategic developments such as key mergers & acquisitions, future capacities, partnerships, financial overviews, collaborations, new product developments, new product launches, and other developments.Get more information on "Global Cetirizine OTC Market Research Report" by requesting FREE Sample Copy at https://www.valuemarketresearch.com/contact/cetirizine-otc-market/download-sampleMarket DynamicsThe rising prevalence of histamine borne allergic diseases drives the global cetirizine OTC market.
It affects about 30-40% of the world population and has become one of the three critical conditions in the 21st century.
Histamine is a significant mediator in allergic diseases.
