Ransomware or WannaCry is a type of malicious software designed to block access to a computer system until a sum of money is paid.
In last few year you can heard news about ransomware virus which locked the computer and files encrypted by malicious programs designed to extort money from users.
Keep in mind, AV is based on signatures so new variants may and will slip through the cracks, but this could easily be a first line of defense.
Make sure all your users understand the dangers of ransomware and how to recognize phishing attempts.
I know this is of course a highly political and even cultural request to make, however reducing privileges will reduce the attack surface significantly.
End users shouldn’t be downloading and installing games anyway, right?