CINCINNATI - Seven years ago Cincinnati Children's scientists first used pluripotent stem cells to mimic natural human development and grow working human intestine in a lab.
Today medical center doctors can bioengineer the gastrointestinal tissues of sick children to find clues about a child's disease and how to treat it.
Organoid technology has the potential to solve several current medical and research challenges, according to Aaron Zorn, PhD, the new organoid center's director.
The technology gives researchers a first-in-class physiological platform for laboratory research on living diseased tissue, which cannot be done on patients.
It can provide laboratory human modeling systems in a petri dish for developing and testing drugs before expensive clinical trials.
The new center is organized to be a highly collaborative, multi-disciplinary center of excellence that integrates scientists, physicians, geneticists, bioengineers and entrepreneurs, according to Zorn.