Carbon-carbon (C-C) bonds make up the skeleton of all organic molecules.
However, creating such ubiquitous C-C bonds artificially is still a complicated task.
In particular, since several molecules used in medicine, pharmacology and material chemistry contain aryl groups, devising a way to efficiently and selectively introduce this chemical group is a major goal for organic chemists.
Currently, most arylation reactions require harsh reaction conditions, including high temperatures and excess additives.
Scientists at the Center for Catalytic Hydrocarbon Functionalization, within the Institute for Basic Science (IBS, South Korea), devised a method to selectively introduce aryl groups into C-H bonds at room temperature.
Published in Nature Chemistry, the study also clarifies the details of this reaction, which turned out to be different from the conventional idea.