Depression is a tricky beast.
Symptoms vary widely from person to person, as does the response to treatment.
But there’s no question that genetic makeup plays an important role, and understanding the genetic architecture of depression could help us better understand how to treat it.
A new study in the journal Nature Genetics has identified 44 genetic variants that can increase the risk of developing major depression.
The authors of the study, which examined the genes of nearly 500,000 people, say their work suggests that all humans may carry at least some of these variants.
The largest study of its kind, the work refines our understanding of the complex ways that genetics impacts mental illness.