Glioblastoma multiforme, a type of brain tumor, is one of the most difficult-to-treat cancers.
Only a handful of drugs are approved to treat glioblastoma, and the median life expectancy for patients diagnosed with the disease is less than 15 months.
MIT researchers have now devised a new drug-delivering nanoparticle that could offer a better way to treat glioblastoma.
The particles, which carry two different drugs, are designed so that they can easily cross the blood-brain barrier and bind directly to tumor cells.
Hammond and Scott Floyd, a former Koch Institute clinical investigator who is now an associate professor of radiation oncology at Duke University School of Medicine, are the senior authors of the paper, which appears in Nature Communications.
The paper's lead author is Fred Lam, a Koch Institute research scientist.