Beagles are shown in this file photo.The study was published online in April, but the fallout is hitting now: University of Missouri-Columbia researchers are trying to identify "painless or non-invasive treatments for corneal injuries," and devised a pilot study using six beagles to that end.The researchers wanted to study the effects of topical hyaluronic acid on corneal ulcers; under sedation, the dogs' left corneas were wounded the New York Daily News reports this blinded them in that eye , with half the group then acting as control and half administered the acid.Per the study, posted by the Journal of Veterinary Opthamology, "No statistical differences ... were found between groups at any tested time point."At its conclusion, the dogs were put down.The Beagle Freedom Project is up in arms over what it says was a flawed study from the outset.
Minority Report depicted a future in which our every move was monitored.Each lingering gaze or blink of an eye was used to serve us the perfect ads.One night in the summer, WIRED got an insight into how this dystopian view of the world might play out.Fitted with eye-tracking goggles and sensors on our hands we ventured into the London Underground.The idea behind the trial was to track not only where we looked, but how we felt about the people, adverts, objects and signs we found ourselves gazing at – even if we consciously didn't realise we were having an emotional response.The eye-tracking goggles – which look a little like Google Glass – used pupil centre corneal reflection PCCR .
Microscopic water-dwelling critters called amoebae are creeping into human eyeballs, with the potential to cause permanent blindness.Acanthamoeba keratitis is a rare disease, but has been documented worldwide, and is typically associated with contact lens use and contaminated swimming pools.Australian researchers reviewed 34 cases in Melbourne that occurred over an 18-year period.Patients presented with eye pain, redness and swelling, a ring-shaped corneal ulcer, and thinning of the eye tissue.An overwhelming number of the cases (86 per cent) occurred in contact lens wearers, six of whom admitted to swimming with their contacts in, while seven said they'd rinsed theirs with tap water.Most of the cases were treated successfully with medication, while a small number required surgery and experienced vision impairment.
Scientists at Newcastle University, UK, and the University of California have developed a new method to grow curved human corneas improving the quality and transparency - solely by controlling the behaviour of cells in a dish.The research publishing today in Advanced Biosystems has revealed that corneal cells isolated from human donors and grown on curved surfaces arrange themselves in a very regular lattice-like organisation.Cells grown this way achieve the precise alignment that gives the human cornea its strength and transparency.Lead researcher Che Connon, Professor of Tissue Engineering at Newcastle University explained: "We discovered that the cells grown on a dome-shaped surface behaved differently than those on flat one, crawling over the dome in a lattice-like structure - similar to a pie crust."These cells then produced large amounts of aligned collagen, the natural fibres that make up the human cornea.This is also the arrangement normally found in the human eye, and there were no easy ways to recreate it in a dish...until now!
Though the Webb telescope will focus on stars and galaxies approximately 13.5 billion light-years away, its sight goes through a similar process as you would if you underwent laser vision correction surgery to be able to focus on an object 10 feet across the room.In orbit at Earth's second Lagrange point (L2), far from the help of a terrestrial doctor, Webb will use its near-infrared camera (NIRCam) instrument to help align its primary mirror segments about 40 days after launch, once they have unfolded from their unaligned stowed position and cooled to their operating temperatures.Laser vision correction surgery reshapes the cornea of the eye to remove imperfections that cause vision problems like nearsightedness.The cornea is the surface of the eye; it helps focus rays of light on the retina at the back of the eye, and though it appears to be uniform and smooth, it can be misshapen and pockmarked with dents, dimples, and other imperfections that can affect a person's sight.The relative positioning of Webb's primary mirror segments after launch will be the equivalent of these corneal imperfections, and engineers on Earth will need to make corrections to the mirrors' positions to bring them into alignment, ensuring they will produce sharp, focused images.These corrections are made through a process called wavefront sensing and control, which aligns the mirrors to within tens of nanometers.
A new method of examining the skin can reduce the number of animal experiments while providing new opportunities to develop pharmaceuticals and cosmetics.Chemical imaging allows all layers of the skin to be seen and the presence of virtually any substance in any part of the skin to be measured with a very high degree of precision.A new study from Chalmers University of Technology and the University of Gothenburg shows how what is termed chemical imaging can provide comprehensive information about the human skin with a very high level of precision.Investigations into how substances pass into and through the skin have so far taken place in two ways: by using tape strips to pull off the top "corneal" layer of skin for analysis, and through urine and blood testing to see what has penetrated through the skin.But we still know very little about what happens in the layers of skin in between.The new method was created when the chemists Per Malmberg, at Chalmers University of Technology, and Lina Hagvall, at the University of Gothenburg, brought their areas of research together.
The blink reflex has been shown to be sensitive to a number of neurological insults, including traumatic brain injury, Parkinson's disease and Huntington's disease, suggesting that it could be a useful tool for neurological assessment.Although electromyography (EMG)-derived time metrics were used to analyze the blink reflex as early as the 1950s, quantitative assessment of the blink response was never adopted widely in clinical practice, in part because existing technology was somewhat cumbersome and uncomfortable.The Blink Reflexometer, a portable device developed by the Zucker Institute for Applied Neurosciences at the Medical University of South Carolina that has since been licensed to BLINKtbi (Charleston, SC), uses high-speed video to capture and quantitatively analyze a series of blinks that it stimulates with puffs of air.In a validation study in ten healthy college students, the results of which were reported in an article published online December 12, 2017 by the IEEE Journal of Translational Engineering in Health and Medicine, a team of investigators at the Medical University of South Carolina and The Citadel obtained blink measurements for ten healthy college students using the Blink Reflexometer and compared them to published measurements obtained with EMG.It's analogous to the difference between saying someone is feverish to measuring the patient's temperature, an objective measurement, with a thermometer."This study was based on a small number of young, healthy patients, so larger studies in participants that better represent the general populace will be required.
The Centers for Disease Control and Prevention estimate that between 1.6 and 3.8 million concussions occur each year in the US.In addition, research indicates that nearly a quarter of annual traumatic brain injuries among children are sustained during high-contact/collision recreational activities or sports.Medical professionals and field-side staff must base concussion-related decisions on overt symptom assessments (e.g., balance, neurocognition) and self-reports that often provide incomplete, misleading or conflicting information."Concussion is a mild traumatic brain injury and we know it's under-reported because, so often, it goes unnoticed or undiagnosed.When a concussion or suspected concussion occurred, participants were re-tested within one to 48 hours after the event to collect post-event blink reflex measurements and standard concussion evaluation protocol results.Control athlete data revealed significant differences in specific blink reflex parameters between baseline and active play.
A 26-year-old Oregon woman has received the undesirable title of the first human to have tiny parasitic worms previously only ever seen in cattle squirming around in her eyeball.Infectious disease experts reported that the woman had a total of 14 of the wriggling parasites pulled from her left eyeball after she experienced eye irritation.This happened in August 2016, although the experts only published their paper on Monday, February 12.The woman pulled most of the worms out herself over a 20-day period, despite visiting several doctors.The translucent worms were less than a half-inch long.Several of the parasites pulled from her peepers were sent to experts at the Centers for Disease Control and Prevention’s Parasitic Diseases Reference Laboratory.
Could the development of eyesight-improving eyedrops help eliminate the need for glasses?A team of ophthalmologists at these institutes have invented and tested “nanodrops” which, combined with a laser process, reportedly results in improvements in both short- and long-sightedness.Clinical testing in humans is set to take place later in 2018.The first of these steps involves an app on the patient’s smartphone or mobile device which measures their eye refraction.A laser pattern is then created and projected onto the corneal surface of the eyes.This surgical procedure takes less than one second.
New York, NY--May 29, 2018--Nearsightedness, or myopia, is an increasing problem around the world.In East Asia, 70 to 90 percent of teenagers and young adults are nearsighted.But, while vision correction surgery has a relatively high success rate, it is an invasive procedure, subject to post-surgical complications, and in rare cases permanent vision loss.Columbia Engineering researcher Sinisa Vukelic has developed a new non-invasive approach to permanently correct vision that shows great promise in preclinical models.His method uses a femtosecond oscillator, an ultrafast laser that delivers pulses of very low energy at high repetition rate, for selective and localized alteration of the biochemical and biomechanical properties of corneal tissue.The technique, which changes the tissue's macroscopic geometry, is non-surgical and has fewer side effects and limitations than those seen in refractive surgeries.
Researchers at the University Of Newcastle have announced they’ve managed to 3D print corneas – the outermost part of the human eye.This is incredible, life-changing news for a lot of folks.Worldwide, 10 million people require surgery to prevent corneal blindness from diseases like trachoma.It works by taking stem cells from a health donor’s cornea and mixing it together with a gel, creating what researchers have deemed “bio-ink.”“Our unique gel – a combination of alginate and collagen – keeps the stem cells alive whilst producing a material which is stiff enough to hold its shape, but soft enough to be squeezed out the nozzle of a 3D printer,” Che Connon, Professor of Tissue Engineering at The University of Newcastle, said.The 3D bio-printer was described as “low-cost” and only took 10 minutes to print a cornea.
Researchers at Newcastle University have been able to 3D-print a biocompatible corneal framework using a new gel formulations that “keeps the stem cells alive whilst producing a material which is stiff enough to hold its shape but soft enough to be squeezed out the nozzle of a 3D printer.”There is a significant shortage of corneas available to transplant, with 10 million people worldwide requiring surgery to prevent corneal blindness as a result of diseases such as trachoma, an infectious eye disorder,” wrote the researchers.“In addition, almost 5 million people suffer total blindness due to corneal scarring caused by burns, lacerations, abrasion or disease.”The product uses “human corneal stromal cells” from a donor cornea mixed with alginate and collagen to create bio-ink that can turn into a living cornea.This means that one donor cornea can help multiple patients.““This builds upon our previous work in which we kept cells alive for weeks at room temperature within a similar hydrogel.
One of the important parts of the eye that allows humans to see is the outer layer known as the cornea.That part of the eye has a key role in focusing.For people with cornea problems, the only hope of clear vision is a cornea transplant from a donor, which are hard to come by.Researchers have now been able to 3D print the first human corneas that could eliminate the shortage.The process mixes together stem cells, specifically human corneal stromal cells, from a healthy donor with alginate and collagen.The solution creates a bio-ink solution that can be used in a 3D printer.
The human eye is a remarkably sophisticated organ and like the lens to a camera, it’s the cornea that focuses the flood of photons into a perceptible image.In the next few years, artificial corneas may become more accessible thanks to new research out of Newcastle University in the United Kingdom.There, researchers mixed stem cells from the cornea of a healthy donor with collagen and algae molecules to create a bio-ink, which they 3D-printed into an artificial cornea.The research is currently just a proof-of-concept but lays the groundwork for future techniques to create low-cost, easy-to-produce bionic eyes.“It needed to be extrudable, or thin enough to push through a thin gauge needle to allow for bio-printing.And the material needed to be stiff enough such that it holds it shape, allowing to build up a 3D cornea.”
Index Markets Research study on Corneal Pachymetry Market has been prepared based on detailed market analysis from industry experts with inputs of the current situation and the development forecasts Market.The key players of Corneal Pachymetry Market include:- Reichert, DGH Technology, Tomey, Micro Medical Devices, NIDEK, Accutome, Sonomed Escalon, OCULUS, Konan Medical, Optovue, Optikon, MEDA Co., Ltd.It includes market dynamics including latest trends, opportunities, market drivers, and challenges.The report covers an overall view of the global Corneal Pachymetry Market and also includes market segments and market size.It provides the compilation of clear data and assessment(qualitative and quantitative) by industry examiners, contributions from industry specialists and industry members across the value chain.The report also maps the qualitative impact of various market factors on market segments and geographies.Geographically, this report is segmented into several key Regions, with Sales, Sales, revenue, Market Share (%) and Growth Rate (%) of Corneal Pachymetry in these regions, from 2013 to 2023 (forecast), covering United States, North America, Europe, Asia-Pacific, South America, Middle East and Africa.Market Segmentation by Type: Handheld Type, Non-handheld Type.Market Segmentation by Application: Glaucoma Diagnosis, Refractive Surgery.TOC of Corneal Pachymetry Market Contains Following Points:– Analysis of Manufacturers with Gross Margin Analysis by Value Chain, Marketing Channel, Marketing & Price Trends and Margin and Factors of Price Change– Market Competition Key Companies (List, Company Profile and Sales Data, Regional Market by Company)– Corneal Pachymetry Market by Type Segment Overview by Market Size and Market Prediction– Corneal Pachymetry Industry Environment, Business Operation, Consumers in Private, Economics and Technology– Corneal Pachymetry Market Overview, Development of Corneal Pachymetry Industry Segment by Cost Analysis with Upstream and Downstream(Sales Revenue, Sales Volume, Price, Cost, Gross Margin)– Region Operation Overview by Regions and by Country and Regional Output ForecastInquiry before Buying Report @ conclusion, The Corneal Pachymetry Market research report is a valuable source of guidance and direction.
Index Markets Research study with title Presbyopia Correction Device Market includes market segments like opportunities, challenges, restraints, technological updates, impact of any regulatory policies.This study will provide you comprehensive outlook on market segmented knowledge by Application, Type and major players.The report provides validated market data with complete assessment of the market and contains Future trend, Current Growth Factors, attentive opinions, facts, historical data, and statistically supported industry data.The key players/manufacturers are listed here AcuFocus, Refocus Group, Revision Optics, Presbia.Request for Sample Report @ Presbyopia Correction Device Market research study based on 5 year history data company overview, recent developments, strategies adopted by the market leaders to ensure growth, sustainability, financial overview and recent developments.The new vendor entrants in the market studies trends and emerging drivers are shaping this industry growth as the study avails you with market characteristics, size and growth, segmentation, regional breakdowns, competitive landscape, shares, trend and strategies for this market to compete with the international vendors based on quality, reliability, and innovations in technology.Geographically, this report is segmented into several key Regions such as North America, China, Europe, Southeast Asia, Japan & India, with production, consumption, revenue (million USD), and market share and growth rate of Global Presbyopia Correction Device in these regions, from 2012 to 2022 (forecast).The Study is segmented by following Product Type: Corneal Inlays, Scleral ImplantsMajor applications/end-users industry are as follows: Age 40-50, Age 50-65, Age above 65The industrial experts covers sources associated industries, and suppliers, service providers, manufacturers, distributors, and organizations related to all segments of the industry’s supply chain.Apart from the mentioned information, volume produced (in kilo tons) and the revenue it generates (in US$) of Presbyopia Correction Device market in 2021 is also explained.
Index Markets Research provides statistical analysis on Global Corneal Graft Rejection Drug Market provides a basic overview of the industry including its definition, applications, and manufacturing technology.The report covers business strategists like major drivers, dynamics, share, segmentation, revenue forecasts, effective growth for the key players and facilitate better decision-making.The report offers the estimations of the size of the market and analysis of the trend based on the pipeline of the Corneal Graft Rejection Drug market.The Key Players mentioned in the report are Circadian Technologies Limited, Gene Signal International SA, Oxford BioMedica Plc, Santen Pharmaceutical Co., Ltd.This report provides a competitive scenario, with a purpose of enlightening new entrants about the possibilities in this Corneal Graft Rejection Drug Market.Get a Sample Copy @ report offers a crucial opinion relating to the global Corneal Graft Rejection Drug market by discussing its segmentation Commercial, Government, Personal.The sectors have been reviewed in terms of the present as well as future trends.
 5 October 2018, The global Tissue Engineering Market stood at USD 5.5 billion in 2015 and is expected to witness considerable growth even over the forecast period (from 2016 to 2024).Growing popularity in a variety of sectors including urological products, neurology, burn treatment etc.Organs developed using this method have high efficiency and durability.Rising applications of this method from surgical treatment of tissues and prosthetics to liver, corneal, cardiac tissue engineering is said to propel the growth from 2016 to 2024.The global market is categorized as applications and regions.The applications include GI & gynecology, cancer, cord blood & cell banking, skin or integumentary, urology, dental, musculoskeletal, spine, orthopedics, neurology, and cardiology & vascular.The sector is further expected to continue leading the market on account of the increased number of bone implants due to accidents as well as a geriatric population base.
Michael Mrochen, PhD, Chairman of the Board of Directors at Vivior, receives the Casebeer Award from the International Society of Refractive Surgery.View the full release here: International Society of Refractive Surgery (ISRS), a partner of the American Academy of Ophthalmology, is the leading worldwide organization for refractive surgeons.Each year, ISRS awards members for their special contributions to the ISRS, as well as their dedication to the field.Michael Mrochen is internationally known for his pioneering work on corneal laser surgery, corneal cross linking, ocular biometry and cornea inlays for presbyopia and hyperopia.Mario Stark, CEO at Vivior, highlights that “we are proud at Vivior that the ISRS recognizes the outstanding work that Michael has done over the decades to advance the treatment options in ophthalmology.