Status Epilepticus (SE) is a medical emergency that refers to a continuous seizure activity lasting for more than 5 minutes, or a series of seizures where the person does not recover consciousness in between. SE can be caused by various factors, such as drug overdose, head trauma, stroke, infections, or brain tumors. It is a life-threatening condition that requires prompt medical intervention to prevent brain damage or even death. In this article, we will discuss the applications and uses of SE. SE is diagnosed by observing the clinical signs and symptoms of continuous seizures or recurrent seizures without recovery. It is confirmed by electroencephalogram (EEG) recordings that show a pattern of continuous seizure activity. EEG monitoring is also used to monitor the response to treatment and the progression of the condition.
SE can be classified into two types: convulsive and non-convulsive. Convulsive SE is characterized by visible seizures that involve shaking, jerking, or loss of consciousness. Non-convulsive SE, on the other hand, may not have any visible seizures but may show subtle changes in mental status, such as confusion, agitation, or staring spells. Knowing the type of SE is important in choosing the appropriate treatment. Status Epilepticus is a medical emergency that requires immediate treatment to prevent brain damage or death. The first line of treatment is the administration of benzodiazepines, such as lorazepam or diazepam, to stop the seizure activity. If the seizures do not stop after benzodiazepines, additional medications, such as phenytoin, fosphenytoin, or levetiracetam, may be given to control the seizures. In refractory cases, anesthesia and intubation may be necessary to control the seizures and protect the airway.
SE is used as a model of epilepsy in animal and human studies. The induction of SE in animal models allows researchers to study the mechanisms and pathophysiology of epilepsy and test new antiepileptic drugs. In human studies, SE can be used to investigate the long-term effects of seizures on the brain and cognitive function. SE is a common topic in medical education, particularly in emergency medicine and neurology. Understanding the diagnosis and treatment of SE is crucial for medical professionals who may encounter patients with SE in the emergency department or intensive care unit. SE is a medical emergency that requires timely and appropriate treatment. Healthcare providers can use SE as a quality improvement measure to evaluate the effectiveness of their treatment protocols and identify areas for improvement.
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Summary Researcher clinical trial report, “Status Epilepticus Global Clinical Trials Review, H1, 2020" provides an overview of Status Epilepticus Clinical trials scenario.
This report provides top line data relating to the clinical trials on Status Epilepticus.
The report offers coverage of disease clinical trials by region, country (G7 & E7), phase, trial status, end points status and sponsor type.
Report also provides prominent drugs for in-progress trials (based on number of ongoing trials).
GlobalData Clinical Trial Reports are generated using proprietary database - Pharma eTrack Clinical trials database.
Clinical trials database undergoes periodic update by dynamic process.
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