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Gabapentin for anxiety has been used in the treatment of anxiety disorders for many years.

The drug is considered relatively non-habit forming.ANCOVA is a clinically proven, low-dose combination of anticonvulsants to relieve the symptoms of generalized anxiety disorder.

In a double-blind, randomized, placebo-controlled study comparing 300mg gabapentin against 900mg gabapentin, subjects were categorized into four groups.

Anxiety, mood, motor functions and sleep were evaluated using the Numeric Test, State-related Assessment Scale (SSA), Positive Cognitive Syndrome Scale (PCAS-R), and Neuropsychological Testing Scale (NTS).Preliminary results from two placebo-controlled studies showed that gabapentin may be useful in the treatment of anxiety and panic disorders.

It was found to be better than benzodiazepines in reducing mental health problems and improving memory, but did not show effective results on patient with neurontinergic disorder and dysthymia.

Gabapentin is mainly used for the relief of muscle spasms and neuralgia due to rheumatoid arthritis.