Protein stability analysis involves techniques that are used to analyze the stability of proteins under different temperatures, pH levels, and other environmental conditions. These techniques help identify conditions under which proteins remain folded into their functional three-dimensional structure. Protein stability analysis finds applications in various areas including biotherapeutic development, food science, and proteome research. Common techniques used in protein stability analysis include Differential Scanning Calorimetry (DSC), which measures the heat required to denature proteins as temperature increases; ThermoFluor, which detects protein unfolding through the use of environmentally sensitive fluorescent dyes; and Dynamic Light Scattering (DLS), which analyzes protein structural changes based on fluctuations in scattered light. The growing demand for biotherapeutics and ongoing proteome research projects have boosted the need for techniques that can provide detailed protein characterization data.
The Global Protein Stability Analysis Market is estimated to be valued at US$ 2.43 BN in 2024 and is expected to exhibit a CAGR of 11% over the forecast period 2024 to 2031.
Key Takeaways
Key players operating in the Protein Stability Analysis Market Demand are Thermo Fisher Scientific, Inc., Enzo Biochem, Inc., PerkinElmer Inc., NanoTemper, GE Healthcare, HORIBA, Ltd., Malvern Panalytical Ltd., Agilent Technologies, Inc., SETARAM Instrumentation, Unchained Labs, Waters Corporation, and Applied Photophysics Ltd. The market leaders are focusing on introducing innovative products and solutions to facilitate robust protein characterization. For instance, in 2022, Malvern Panalytical launched the Spectrasize 300, an advanced DLS system for easy characterization of particle size distribution in liquid samples.
The demand for protein stability analysis is surging globally due to the increasing investments in proteomics research and development by pharmaceutical and biotechnology companies. Rapid advancements in analytical technologies are further supporting comprehensive protein study. Additionally, growing awareness about protein stabilization importance in ensuring biologic drug efficacy and safety is driving the adoption of protein stability analysis solutions.
The protein stability analysis market is also witnessing rising growth opportunities across the globe with market players strategizing global expansion. For instance, in 2022, NanoTemper entered into a partnership with Sysmex to distribute its protein characterization instruments in the Japanese market. Similarly, SETARAM Instrumentation strengthened its presence in South and East Asia through new distributor agreements. The ongoing international collaborations and geographic expansions are expected to help vendors tap into new revenue pools.
Market drivers
The key driver fueling the growth of the protein stability analysis market is the robust investments in proteomics research by biopharmaceutical and biotechnology companies. Understanding protein stability mechanisms allows for developing highly effective and safe biologic drugs. Furthermore, ongoing innovations in analytical techniques such as DSC and DLS that provide high-resolution stability data at elevated temperatures and varied pH levels are supporting comprehensive protein characterization. Rising R&D expenditures on biosimilars development and demand for characterization of protein aggregation tendencies are also propelling the adoption of protein stability analysis solutions.
The current geopolitical instability across various regions is negatively impacting the growth of the global protein stability analysis market. The ongoing Russia-Ukraine war and rising tensions between major world powers have disrupted global supply chains and international trade. This has led to shortages of raw materials and components required for manufacturing protein stability analysis instruments and consumables. Additionally, economic sanctions imposed by Western nations on Russia in response to its invasion of Ukraine are hindering collaboration and partnership opportunities between life sciences companies. The conflict has also pushed up energy and transportation costs globally. This is increasing the operating expenditure of players in the protein stability analysis market, thus squeezing their profit margins. Furthermore, political instability and economic uncertainty in several countries have weakened research funding for the academic and biopharmaceutical sectors. This is expected to negatively impact the demand for protein stability analysis tools in the coming years. However, the market is anticipated to rebound once the geopolitical issues are resolved and international relations stabilize. Alternative sourcing, price hikes, and cost optimization strategies by market participants could also help overcome these short term challenges.
North America currently dominates the global protein stability analysis market and holds the largest share in terms of value. This is chiefly attributed to well-established pharmaceutical and biotechnology industries, high R&D expenditure, rising outsourcing activities of stability testing, and the presence of key players in the region. The strong foothold of global leaders such as Thermo Fisher Scientific and Waters Corporation in the US and Canada is driving the protein stability analysis market growth in North America. Europe holds the second largest market share owing to strong government support for life science research and rising pharmaceutical production. The rising pharmaceutical outsourcing sector in UK, Germany, and France is bolstering the regional market growth. The Asia Pacific region is demonstrating high growth potential and emerging as a major investment hotspot for global life sciences majors. This is owing to increasing biopharmaceutical R&D expenditure, growing elderly population, and supportive government policies promoting innovation. China, Japan, and India are some of the most lucrative protein stability analysis markets in Asia Pacific.
The Asia Pacific region is poised to register the highest growth in the global protein stability analysis market during the forecast period. This can be attributed to several factors such as expanding biopharmaceutical industry, improving healthcare infrastructure, rising investments by market players, and increasing government funding for life sciences research and development. In particular, China and India present immense opportunities for players operating in the protein stability analysis market. These countries are witnessing strong economic development which is increasing their healthcare expenditure and modernizing their research capabilities. Additionally, they offer competitive manufacturing and operation costs which are attracting several multinational corporations to establish their manufacturing facilities and R&D centers in Asia Pacific. This is significantly boosting the regional market for protein stability analysis instruments and services. Furthermore, the rapidly aging demography of countries like Japan and China is augmenting the demand for novel biologics and biosimilars. This is anticipated to drive the uptake of protein stability analysis techniques for ensuring long-term stability and efficacy of biopharmaceutical formulations.
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The report presents key statistical data about the Protein Stability Analysis market for the forecast timeline of 2020-2027, covering historical analysis, demands and supply dynamics, current and emerging trends, and revenue estimations.
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The report strives to provide an accurate estimation of the market trends for the Protein Stability Analysis market from the year 2020 to the year 2027.
The research report consists of a complete market analysis, including financial standing, revenue estimation, limitations, and dynamics that might affect the market.The report is generated according to the latest economic landscape in tune with the COVID-19 crisis.
The pandemic has affected the global economic scenario, and the report provides details about its impact on the overall industry.
Global Protein Stability Analysis Market was valued US$ 1.51billion in 2018 and is expected to reach US$ 3.8 billion by 2026, at CAGR of 12.32 %during forecast period.
The Global Protein Stability Analysis Market research report offers accurate insights for the growth prospects of the Protein Stability Analysis market in the forecast years 2020-2027.
The report is an all-inclusive study of the Protein Stability Analysis market that offers the readers a better view of the current and emerging market trends through a thorough analysis of the market size, growth trends, supply and demand ratio, market share, sales network and distribution channels, and other key elements.Furthermore, the report is furnished with the current market scenario with regards to the COVID-19 pandemic.
The global public health emergency has disrupted the lives of everyone across the globe.
It has also had a substantial impact on the Protein Stability Analysis industry as global supply chains have been disrupted, and the financial scenario is tight.
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