POCT (Point-of-Care Testing) refers to clinical and bedside testing conducted in close proximity to patients. It is often not performed by clinical laboratory personnel. POCT holds significant importance in disease prevention, etiology determination, prognosis, enhancing treatment outcomes, and reducing healthcare expenses. It meets clinical testing needs across various healthcare settings. POCT serves as a complement to traditional laboratory testing methods. It is characterized by short testing times, spatial flexibility, and simple operation.
However, as it is decentralized, the accuracy of test results in POCT can be greatly affected by non-standardized procedures and inadequate quality control. The field of POCT products has advanced through four generations: qualitative, semi-quantitative, fully quantitative, and automated, due to the continuous innovation in testing technologies. POCT technical principles include dry chemistry, colloidal gold, immunofluorescence, microfluidic chips, chemiluminescence, biosensors, and biochips.
Colloidal gold is the most commonly used nanoparticle for optical labeling due to its ease of use, biocompatibility, and high visibility. It appears deep red in color, which can cause confusion in on-site testing as it displays the same color in two or more test lines. Polystyrene particles (PS particles), also referred to as latex beads (LBs), impregnated with various bright dyes have several advantages. They are easy to synthesize and have multi-color capability, making them an ideal choice for developing robust immunochromatographic analysis.
CD Bioparticles offers a variety of uniform and monodisperse colored polystyrene particles, including Diagpoly™ Colored Polystyrene Particles. These particles are highly pigmented, which can improve visual detection in assays such as latex agglutination, dipstick, and membrane-based assays.
Advantages of Colored Polystyrene Particles for POCT
Simplicity and speed: In contrast to colloidal gold and fluorescent nanoparticles, colored polystyrene nanoparticles can be prepared by copolymerization with dyes, solvent swelling of templated nanoparticles and self-assembly of block copolymers and dyes, providing various surface functional groups. In addition, polystyrene nanoparticles exhibit excellent biocompatibility and flexibility, facilitating effective conjugation with specific proteins and antibodies.
Increased sensitivity and specificity: Each particle of colored polystyrene nanoparticles is carefully designed in size and coated with specific ‘capture molecules’ designed to trap their intended targets. When samples containing target molecules are introduced, these coated particles act like magnets, attracting their specific targets with high affinity. This targeted binding significantly reduces the chance of capturing the wrong molecules, thus minimizing false positives. The large surface area of the polystyrene particles allows more capture molecules to be accommodated, increasing test sensitivity and minimizing false negatives. Polystyrene itself plays a critical role in detection accuracy. This robust material is chemically inert, meaning it does not interfere with the binding process or produce false signals. In addition, its uniform surface provides a stable platform for capture molecule attachment, ensuring consistent and reliable results.
Versatility and multiplex detection: While LFTs are typically designed for the rapid detection of single analytes per assay, there is growing interest in multiplex analysis due to its potential for increased throughput, reduced sample requirements and improved assay efficiency. The most common approach to achieving multiplex detection in LFTs is to use multiple test lines on the test strip, each reporting the detection results of specific analytes. Although colloidal gold has a distinct red color, it is limited to single color testing and is not suitable for multiplexing. In contrast, colored latex beads offer a variety of vivid colors for easier visual assessment of multiple test lines, reducing the risk of misinterpretation of results.
Cost-effectiveness: Test strips produced with colored latex beads from different batches have relatively little variation between batches, and production processes typically require minimal or no adjustment. Colloidal gold readily adsorbs to certain materials, even when glass containers are used, which introduces unavoidable risks in large-scale production. Therefore, a more cautious approach is to opt for colored latex particles. The use of colored latex particles in the production of immunochromatographic test strips is therefore more cost effective.
Customization and flexibility: Through unique surface modification processes, CD Bioparticles can add different functional groups to the surface of colored latex particles, such as carboxyl and amine groups, to facilitate antibody/antigen coupling on microsphere surfaces. Carboxyl-modified colored latex particles introduce more N and O atoms onto the microsphere surface, increasing the rate of antibody migration to the material surface and effectively improving the coupling efficiency. Our microspheres feature uniform particle sizes, stable and controllable surface functional groups and excellent experimental reproducibility. CD Bioparticles can customize colored latex particles with various functional group surface modifications according to customer requirements.
Features of CD Bioparticles' Colored PS Particles
Our monodisperse-colored polystyrene latex microspheres have perfect sphericity and narrow size distribution. With a wide size range from 30 nm to 750 µm, they have larger diameters compared to colloidal gold particles typically used in immunochromatography products (colored latex microspheres from 200 nm to 400 nm, colloidal gold particle sizes from 20-40 nm), offering higher relative sensitivity.
Shop for DiagPoly™ Colored Polystyrene Particles, 200 nm to 400 nm.
We offer a variety of vividly colored latex particles including black, blue, green, orange, red, purple and yellow. With enhanced coloring capabilities, results are more visually intuitive, allowing for easy visual interpretation or multiplexed analysis.
Also, this report covers market segmentation by major market verdors, types, applications/end users and geography(North America, East Asia, Europe, South Asia, Southeast Asia, Middle East, Africa, Oceania, South America).Download FREE Sample of this Report @ https://www.24chemicalresearch.com/download-sample/98551/global-black-particles-2021-215 The Black Particles are produced by torrefaction or steam explosion, during which the water content, cellulose sugar and other volatile organic compounds are removed from the biomass to produce solid biofuels with similar characteristics to fossil coal.The global Black Particles market was valued at 77.9 Million USD in 2020 and will grow with a CAGR of 14.55% from 2020 to 2027, based on Our Researcher newly published report.The main difference between the black particles and the standard wood particles is that the volume energy density of the black particles is 30% higher, the biodegradation is less, the transportation is safer and hydrophobic.Black particles have excellent energy and processing quality, and are renewable, suitable for basic loading and dispatching according to needs, and will slowly replace coal products.
The black particles are 100% biomass particles without additives, with excellent energy content and processing quality.
It has unique water resistance and durability.
Global Black Particles key players include Zilkha Biomass Energy, Bionet, Blackwood Technology, Arbaflame, Airex Energy, etc.
And in terms of application, the largest application is Power Generation, followed by Others.By Market Verdors:Zilkha Biomass EnergyNew Biomass EnergyBionetBlackwood TechnologyArbaflameAirex EnergyBioendevECNBy Types:BakingSteam ExplosionBy Applications:Power GenerationKey Indicators AnalysedMarket Players & Competitor Analysis: The report covers the key players of the industry including Company Profile, Product Specifications, Production Capacity/Sales, Revenue, Price and Gross Margin 2016-2027 & Sales with a thorough analysis of the market’s competitive landscape and detailed information on vendors and comprehensive details of factors that will challenge the growth of major market vendors.Global and Regional Market Analysis: The report includes Global & Regional market status and outlook 2016-2027.
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COVID-19 Impact Analysis on Polystyrene Foam Market report published by Value Market Research provides a detailed market analysis comprising market size, share, value, growth and trends for the period 2020-2027.
Moreover, this market report also covers regional and country markets in detail.The research report also covers the comprehensive profiles of the key players in the market and an in-depth view of the competitive landscape worldwide.
This section consists of a holistic view of the competitive landscape that includes various strategic developments such as key mergers & acquisitions, future capacities, partnerships, financial overviews, collaborations, new product developments, new product launches, and other developments.Get more information on "Global Polystyrene Foam Market Research Report" by requesting FREE Sample Copy at https://www.valuemarketresearch.com/contact/polystyrene-foam-market/download-sampleMarket DynamicsThe market is driven by the rising prominence of insulation property in the construction industry of developed regions, including China and India, which is expected to aid the usage of high-quality polymers.
Further, growing demand for cold chain packaging in the pharmaceutical sector to increase product safety, lifespan and maintain the freshness of products in the food and beverage sector during transportation is expected to boost the growth of the market.
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This report focuses on Energy Efficient Material volume and value at global level, regional level and company level.
From a global perspective, this report represents overall Energy Efficient Material market size by analyzing historical data and future prospect.
Regionally, this report focuses on several key regions: North America, Europe, China and Japan.The global Energy Efficient Material market is valued at million US$ in 2018 is expected to reach million US$ by the end of 2025, growing at a CAGR of during 2019–2025.At company level, this report focuses on the production capacity, ex-factory price, revenue and market share for each manufacturer covered in this report.Download FREE Sample of this Report @ https://www.grandresearchstore.com/report-sample/global-energy-efficient-material-2019-720The following manufacturers are covered:Cornerstone Industrial Mineral CorporationPPG IndustriesSaint-GobainAustralian PerliteWorld MineralsLoyal GroupIneos GroupAsahi Fiber GlassAmeron InternationalChina FiberglassSegment by RegionsNorth AmericaEuropeChinaJapanSegment by TypePolyisocyanurateExtruded PolystyreneExpanded PolystyreneFiberglassCelluloseMineral WoolOthersSegment by ApplicationCommercial BuildingIndustrial BuildingCivil BuildingResidenceGet the Complete Report & TOC @ https://www.grandresearchstore.com/chemicals-and-materials/global-energy-efficient-material-2019-720Table of contentExecutive Summary1 Energy Efficient Material Market Overview1.1 Product Overview and Scope of Energy Efficient Material1.2 Energy Efficient Material Segment by Type1.2.1 Global Energy Efficient Material Production Growth Rate Comparison by Type (2014–2025)1.2.2 Polyisocyanurate1.2.3 Extruded Polystyrene1.2.4 Expanded Polystyrene1.2.5 Fiberglass1.2.6 Cellulose1.2.7 Mineral Wool1.2.8 Others1.3 Energy Efficient Material Segment by Application1.3.1 Energy Efficient Material Consumption Comparison by Application (2014–2025)1.3.2 Commercial Building1.3.3 Industrial Building1.3.4 Civil Building1.3.5 Residence1.3 Global Energy Efficient Material Market by Region1.3.1 Global Energy Efficient Material Market Size Region1.3.2 North America Status and Prospect (2014–2025)1.3.3 Europe Status and Prospect (2014–2025)1.3.4 China Status and Prospect (2014–2025)1.3.5 Japan Status and Prospect (2014–2025)1.3.6 Southeast Asia Status and Prospect (2014–2025)1.3.7 India Status and Prospect (2014–2025)1.4 Global Energy Efficient Material Market Size1.4.1 Global Energy Efficient Material Revenue (2014–2025)1.4.2 Global Energy Efficient Material Production (2014–2025)CONTACT US:276 5th Avenue, New York , NY 10001,United StatesInternational: (+1) 646 781 7170 / +91 8087042414Email: [email protected] Us On linkedin :- https://www.linkedin.com/company/grand-research-store/
